Evidence map›Paper›PMID 35295223›Full record

ReviewFrontiers in toxicology2022

Methodological Approaches To Assess Innate Immunity and Innate Memory in Marine Invertebrates and Humans.

Manon Auguste, Daniela Melillo, Annunziata Corteggio, Rita Marino, Laura Canesi, Annalisa Pinsino, Paola Italiani, Diana Boraschi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Manon AugusteDepartment of Earth, Environment and Life Sciences, University of Genova, Genova, Italy.
Daniela MelilloInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Annunziata CorteggioInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Rita MarinoStazione Zoologica Anton Dohrn, Napoli, Italy.
Laura CanesiDepartment of Earth, Environment and Life Sciences, University of Genova, Genova, Italy.
Annalisa PinsinoInstitute of Translational Pharmacology (IFT), CNR, Palermo, Italy.
Paola ItalianiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Diana BoraschiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Institute of Cell Biology and Neurobiology · ITUniversity of Genoa · ITIstituto di Farmacologia Traslazionale · ITNational Research Council · ITStazione Zoologica Anton Dohrn · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessing the impact of drugs and contaminants on immune responses requires methodological approaches able to represent real-life conditions and predict long-term effects. Innate immunity/inflammation is the evolutionarily most widespread and conserved defensive mechanism in living organisms, and therefore we will focus here on immunotoxicological methods that specifically target such processes. By exploiting the conserved mechanisms of innate immunity, we have examined the most representative immunotoxicity methodological approaches across living species, to identify common features and human proxy models/assays. Three marine invertebrate organisms are examined in comparison with humans,

Indexed as

humansinnate immunityinnate memoryinvertebratesin vitroin vivo

Identifiers

PMID35295223
PMCPMC8915809
OpenAlexW4213318637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.