Evidence map›Paper›PMID 35295128›Full record

ArticleFrontiers in toxicology2021

Multi-Spectroscopic and Molecular Simulation Approaches to Characterize the Intercalation Binding of 1-Naphthaleneacetic Acid With Calf Thymus DNA.

Xing Hu, Xiaoqiao Luo, Zhisheng Zhou, Rui Wang, Yaqin Hu, Guimei Zhang, Guowen Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. The Effects of NAA on the Tuberous Root Yield and Quality ofCurrent issues in molecular biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xing HuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Xiaoqiao LuoState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Zhisheng ZhouState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Rui WangState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Yaqin HuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Guimei ZhangState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
Guowen ZhangState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, China.
State Key Laboratory of Food Science and Technology · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1-Naphthaleneacetic acid (NAA), having high-quality biological activity and great yield-increasing potential in agricultural production, is a broad-spectrum plant growth regulator. Although NAA is of low toxicity, it can affect the balance of the human metabolism and damage the body if it is used in high quantity for a long time. In this study, the interaction of NAA with calf thymus DNA (ctDNA) was investigated under simulated human physiological acidity (pH 7.4) using fluorescence, ultraviolet-visible absorption, and circular dichroism spectroscopy combined with viscosity measurements and molecular simulation techniques. The quenching of the endogenous fluorescence of NAA by ctDNA, observed in the fluorescence spectrum experiment, was a mixed quenching process that mainly resulted from the formation of the NAA-ctDNA complex. NAA mainly interacted with ctDNA through hydrophobic interaction, and the binding constant and quenching constant at room temperature (298 K) were 0.60 × 10

Indexed as

1–naphthaleneacetic acidcalf thymus DNAintercalationmolecular dockingspectroscopic analysis

Identifiers

PMID35295128
PMCPMC8915802
OpenAlexW3159852452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.