ArticleFrontiers in toxicology2021
Current Insights into Potential Effects of Micro-Nanoplastics on Human Health by
Article in Frontiers in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Lifecycle Implications of Poly(vinyl chloride) (PVC) Micro(nano)plastics (MNPs): Interactions with Coexposed Environmental Pollutants (EPs) and Impact on Their Toxicity and Bioavailability.Environmental science & technology · 2026Article
- Micro- and nanoplastic exposure as an emerging risk factor for depressive-like phenotypes across species: a systematic review.Frontiers in toxicology · 2026Review
- Irreversible Plastic Flows and Sedimentary Ecological Entrapment: A Critical Review of Legacy Risks and Governance Strategies for Planetary Health.Nanomaterials (Basel, Switzerland) · 2025Review
- Global Research Trends on Nanoplastics in Food: A Bibliometric Analysis of Human Health Concerns.Foods (Basel, Switzerland) · 2025Article
- Cheminformatics Approaches to the Analysis of Additives for Sustainable Polymeric Materials.Polymers · 2025Article
- Selective Modification of the Product Profile of Biocatalytic Hydrolyzed PET via Product-Specific Medium Engineering.ChemSusChem · 2025Article
- Micro- and Nano-Plastic-Induced Adverse Health Effects on Lungs and Kidneys Linked to Oxidative Stress and Inflammation.Life (Basel, Switzerland) · 2025Review
- Exposure of Polystyrene Nano- and Microplastics in Increasingly Complex In Vitro Intestinal Cell Models.Nanomaterials (Basel, Switzerland) · 2025Article
- Microplastics - A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms.Cell biochemistry and biophysics · 2024Review
- Polystyrene Nano- and Microplastic Particles Induce an Inflammatory Gene Expression Profile in Rat Neural Stem Cell-Derived Astrocytes In Vitro.Nanomaterials (Basel, Switzerland) · 2024Article
- The potential impacts of micro-and-nano plastics on various organ systems in humans.EBioMedicine · 2024Review
- Assessing the Impact of Polyethylene Nano/Microplastic Exposure on Human Vaginal Keratinocytes.International journal of molecular sciences · 2023Article
- Personal protective equipment and micro-nano plastics: A review of an unavoidable interrelation for a global well-being hazard.Hygiene and environmental health advances · 2023Review
- Physicochemical characterization and quantification of nanoplastics: applicability, limitations and complementarity of batch and fractionation methods.Analytical and bioanalytical chemistry · 2023Article
- Article
- Entropy and Fractal Techniques for Monitoring Fish Behaviour and Welfare in Aquacultural Precision Fish Farming-A Review.Entropy (Basel, Switzerland) · 2023Review
- Impact of Micro- and Nanoplastics on Mitochondria.Metabolites · 2022Review
- The Biological Effects of Polystyrene Nanoplastics on Human Peripheral Blood Lymphocytes.Nanomaterials (Basel, Switzerland) · 2022Article
- Impacts of microplastics on immunity.Frontiers in toxicology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans are exposed to micro and nanoplastics (MNPLs) through inhalation, ingestion and, to a lesser extent, dermal contact. In recent years, new insights indicate the potential of MNPLs to cause damages to human health. Particle toxicity can include oxidative stress, inflammatory lesions, and then increased internalization or translocation through tissues. On the other hand, plastic additives are used in plastic particles, once internalized, can release toxic substances. It is noteworthy that the potential effects of MNPLs encompass a wide range of polymers and chemical additives, showing various physicochemical and toxicological properties, and the size, shape and surface properties are other variables influencing their effects. In spite of the research carried out recently, MNPLs research is in its early stages, and further investigation is required. In this review article, the knowledge of human exposure routes and the recent results on the toxicological effects of MNPLs in human health are presented and discussed. Finally, the current limitations and the main gaps in the body of knowledge are summarised.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.