Evidence map›Paper›PMID 35295086›Full record

ArticleACS medicinal chemistry letters2022

Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.

Rachel Berndsen, Taylor Cunningham, Lauren Kaelin, Makayla Callender, W Dexter Boldog, Brianna Viering, Ashley King, Najwa Labban, Julie A Pollock, Heather B Miller and 1 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Loratadine decreases virulence of methicillin-resistantbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Loratadine Combats Methicillin-ResistantACS infectious diseases · 2024
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rachel BerndsenDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Taylor CunninghamDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Lauren KaelinDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Makayla CallenderDepartment of Chemistry, University of Richmond, Richmond, Virginia 23173, United States.
W Dexter BoldogDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Brianna VieringDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Ashley KingDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.
Najwa LabbanDepartment of Chemistry, University of Richmond, Richmond, Virginia 23173, United States.
Julie A PollockDepartment of Chemistry, University of Richmond, Richmond, Virginia 23173, United States.ORCID https://orcid.org/0000-0003-0153-9991
Heather B MillerDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.ORCID https://orcid.org/0000-0003-1400-7716
Meghan S BlackledgeDepartment of Chemistry, High Point University, High Point, North Carolina 27268, United States.ORCID https://orcid.org/0000-0001-9632-0567
High Point University · USUniversity of Richmond · US

Funding

Use of a novel tricyclic Stk1 inhibitor to uncover molecular mechanism in clinically relevant strains of S. aureusR15GM134503 · NIGMS · HIGH POINT UNIVERSITY · PI Heather B Miller · 2019 to 2026
$1.4M
NIGMS NIH HHS R15 GM134503
6 · The paper itself

Abstract

Antibiotic-resistant infections are a pressing global concern, causing millions of deaths each year. Methicillin-resistant

Identifiers

PMID35295086
PMCPMC8919279
OpenAlexW4210926897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.