Evidence map›Paper›PMID 35295013›Full record

ReviewThe Indian journal of medical research2021

Updates on systemic therapy for cervical cancer.

Paul Gopu, Febin Antony, Sunu Cyriac, Katherine Karakasis, Amit M Oza

Open access · diamondAbstract readReview
In one paragraph

Review in The Indian journal of medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
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  16. Cervical cancer treatment and nursing considerations: Best practices for effective care.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Paul GopuDepartment of Radiation Oncology, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
Febin AntonyDepartment of Radiation Oncology, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
Sunu CyriacDepartment of Medical Oncology & Haematology, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
Katherine KarakasisDivision of Medical Oncology & Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Amit M OzaDivision of Medical Oncology & Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Amala Institute of Medical Sciences · INPrincess Margaret Cancer Centre · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is one of the most common cancers in the world both in terms of incidence and mortality, more so important in low- and middle-income countries. Surgery and radiotherapy remain the backbone of treatment for non-metastatic cervical cancer, with significant improvement in survival provided by addition of chemotherapy to radiotherapy. Survival as well as quality of life is improved by chemotherapy in metastatic disease. Platinum-based chemotherapy with/without bevacizumab is the mainstay of treatment for metastatic disease and has shown improvement in survival. The right combinations and sequence of treatment modalities and medicines are still evolving. Data regarding the molecular and genomic biology of cervical cancer have revealed multiple potential targets for treatment, and several new agents are presently under evaluation including targeted therapies, immunotherapies and vaccines. This review discusses briefly the current standards, newer updates as well as future prospective approaches in systemic therapies for cervical cancer.

Indexed as

Uterine Cervical NeoplasmsBevacizumabFemaleHumansImmunotherapyQuality of LifeBevacizumabCervical cancerimmunotherapysystemic therapytargeted therapyupdate

Identifiers

PMID35295013
PMCPMC9131767
OpenAlexW4285686073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.