Evidence map›Paper›PMID 35294979›Full record

ArticleBrain imaging and behavior2022

Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson's disease.

Eva M Müller-Oehring, Jui-Yang Hong, Kathleen L Poston, Helen M Brontë-Stewart, Edith V Sullivan, Lawrence McGlynn, Tilman Schulte

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain imaging and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eva M Müller-OehringNeuroscience Program, Center for Health Sciences, Biosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA, 94025, USA.
Jui-Yang HongNeuroscience Program, Center for Health Sciences, Biosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA, 94025, USA.
Kathleen L PostonDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Helen M Brontë-StewartDepartment of Neurology & Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Edith V SullivanDepartment of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Lawrence McGlynnDepartment of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Tilman SchulteNeuroscience Program, Center for Health Sciences, Biosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA, 94025, USA. til@stanford.edu.ORCID http://orcid.org/0000-0003-4372-3535
Stanford University · USSRI International · US

Funding

TRACKING HIV INFECTION AND ALCOHOL ABUSE CNS COMORBIDITY WITH NEUROIMAGINGU01AA017347 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, SULLIVAN, EDITH VIONI · 2007 to 2021
$16.0M
CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISMR01AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI, ZAHR, NATALIE M · 1996 to 2025
$8.3M
Working Memory in Parkinson Disease: A Cognitive & Systems Neuroscience ApproachP50AG047366 · NIA · STANFORD UNIVERSITY · PI TIAN, LU · 2015 to 2019
$7.9M
Cerebellar Structure and Function in AlcoholismR37AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2010 to 2019
$5.4M
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingR01AA017347 · NIAAA · SRI INTERNATIONAL · PI Adolf Pfefferbaum · 2022 to 2026
$5.2M
Neurodegeneration and Brain Function in Aging with HIV and Parkinson's DiseaseR01AA023165 · NIAAA · SRI INTERNATIONAL · PI SCHULTE, TILMAN · 2014 to 2017
$3.0M
Basal Ganglia Modulation of Cognitive Systems in Parkinson's diseaseK23NS075097 · NINDS · STANFORD UNIVERSITY · PI POSTON, KATHLEEN LOMBARD · 2011 to 2015
$936k
NIAAA NIH HHS AA010723NIAAA NIH HHS AA017347NIAAA NIH HHS AA023165NIAAA NIH HHS R01 AA010723NIAAA NIH HHS R01 AA017347NIAAA NIH HHS R01 AA023165NIAAA NIH HHS R37 AA010723NIAAA NIH HHS U01 AA017347NIA NIH HHS AG047366NIA NIH HHS P50 AG047366NINDS NIH HHS K23 NS075097NINDS NIH HHS NS075097
6 · The paper itself

Abstract

Expression of executive dysfunctions is marked by substantial heterogeneity in people living with HIV infection (PLWH) and attributed to neuropathological degradation of frontostriatal circuitry with age and disease. We compared the neurophysiology of executive function in older PLWH and Parkinson's disease (PD), both affecting frontostriatal systems. Thirty-one older PLWH, 35 individuals with PD, and 28 older healthy controls underwent executive task-activated fMRI, neuropsychological testing, and a clinical motor exam. fMRI task conditions distinguished cognitive control operations, invoking a lateral frontoparietal network, and motor control operations, activating a cerebellar-precentral-medial prefrontal network. HIV-specific findings denoted a prominent sensorimotor hypoactivation during cognitive control and striatal hypoactivation during motor control related to CD4

Indexed as

HIV InfectionsParkinson DiseaseAgedExecutive FunctionHumansMagnetic Resonance ImagingNeuropsychological TestsAgingExecutive functionHIV infectionParkinson’s diseaseTask-activated fMRI

Identifiers

PMID35294979
PMCPMC10124990
OpenAlexW4220996844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.