Evidence map›Paper›PMID 35294748›Full record

ArticleJournal of nephrology2022

Long-lasting clinical symptoms 6 months after COVID-19 infection in the French national cohort of patients on dialysis.

Mohamed Belkacemi, Hayet Baouche, Sébastien Gomis, Mathilde Lassalle, Cécile Couchoud, REIN registry

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mohamed BelkacemiPRECIS, Nouvelles Technologies, Languedoc Mutualité, Montpellier, France.
Hayet BaoucheBiostatistics Unit, APHP-Necker Enfants Malades Hospital, Paris, France.
Sébastien GomisNephrology Department, University of Lille, CHU Lille, Lille, France.
Mathilde LassalleCoordination Nationale de REIN, Agence de la Biomédecine Langue, REIN Registry, 1 avenue du Stade de France, 93212, Saint Denis La Plaine Cedex, France.
Cécile CouchoudCoordination Nationale de REIN, Agence de la Biomédecine Langue, REIN Registry, 1 avenue du Stade de France, 93212, Saint Denis La Plaine Cedex, France. cecile.couchoud@biomedecine.fr.
REIN registry
Agence de la Biomédecine · FRCentre Hospitalier Universitaire de Lille · FRHôpital Necker-Enfants Malades · FRLanguedoc Mutualité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystematic reviews have shown a high prevalence of long-term persistent sequelae after COVID-19. The aim of this study was to describe the prevalence and risk factors associated with long-lasting clinical symptoms (LLCS) in survivors on chronic dialysis at 6 months after the onset of acute COVID-19 infection in the pre-vaccination period.

methodsThis national cohort study included all French patients on dialysis who had SARS-Cov-2 infection between March and December 2020 and who were alive and still on dialysis 6 months after infection. A form was filled in at 6 months concerning the presence of the following persistent symptoms: extreme fatigue, headache, muscle or weight loss of > 5%, respiratory sequelae, tachycardia, chest pain, joint or muscle pain, persistent anosmia or ageusia, diarrhea, sensory disorders, neuro-cognitive disorders, post-traumatic stress syndrome, depression, and anxiety.

resultsComplete survey results were available for 1217 patients (25.2% of those included); 216 (17.7%) had some LLCS. Probability of 6-month LLCS was higher in patients who were hospitalized in a medical or intensive care unit: OR 1.64 (95% CI 1.16-2.33) and 5.03 (2.94-8.61), respectively. Younger patients had a lower probability of LLCS. Each year on dialysis, as well as diabetes, overweight or obesity were associated with a higher probability of LLCS by 1.03 (1.01-1.06), 1.53 (1.08-2.17), 1.96 (1.10-3.52) and 2.35 (1.30-4.26), respectively.

conclusionsThis national study shows that at least one in six patients on dialysis who have COVID-19 will have LLCS. Systematic screening in dialysis patients would allow us to identify those who need more careful prevention and long-term care and to address them towards a rehabilitation pathway.

Indexed as

COVID-19Cohort StudiesDisease ProgressionFatigueHumansRenal DialysisSARS-CoV-2Cohort-registryDialysisSARS-Cov-2Sequelae

Identifiers

PMID35294748
PMCPMC8924724
OpenAlexW4221098181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.