Evidence map›Paper›PMID 35294678›Full record

ArticleMetabolic brain disease2022

Nobiletin prevents amyloid β

Reihaneh Ghasemi-Tarie, Zahra Kiasalari, Marzieh Fakour, Maryam Khorasani, Sedigheh Keshtkar, Tourandokht Baluchnejadmojarad, Mehrdad Roghani

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

  1. Antiepileptic and antiepileptogenic effects ofIBRO neuroscience reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Reihaneh Ghasemi-TarieDepartment of Physiology, School of Medicine, Shahed University, Tehran, Iran.
Zahra KiasalariNeurophysiology Research Center, Department of Physiology, Shahed University, Tehran, Iran.
Marzieh FakourDepartment of Physiology, School of Medicine, Shahed University, Tehran, Iran. ma.fakour@gmail.com.
Maryam KhorasaniDepartment of Physiology, School of Medicine, Shahed University, Tehran, Iran.
Sedigheh KeshtkarDepartment of Physiology, School of Medicine, Shahed University, Tehran, Iran.
Tourandokht BaluchnejadmojaradDepartment of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mehrdad RoghaniNeurophysiology Research Center, Department of Physiology, Shahed University, Tehran, Iran. mroghani@shahed.ac.ir.ORCID http://orcid.org/0000-0002-9209-8484
Shahed University · IRIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is presented as an age-related neurodegenerative disease with multiple cognitive deficits and amyloid β (Aβ) accumulation is the most important involved factor in its development. Nobiletin is a bioflavonoid isolated from citrus fruits peels with anti-inflammatory and anti-oxidative activity as well as anti-dementia property that has shown potency to ameliorate intracellular and extracellular Ab. The aim of the present study was to assess protective effect of nobiletin against Aβ

Indexed as

Alzheimer DiseaseCognitive DysfunctionNeurodegenerative DiseasesAmyloid beta-PeptidesAnimalsFlavonesHippocampusMaze LearningNeuroinflammatory DiseasesNF-E2-Related Factor 2NF-kappa BNitrosative StressOxidative StressPeptide FragmentsRatsToll-Like Receptor 4Amyloid beta-PeptidesFlavonesNF-E2-Related Factor 2NF-kappa BnobiletinPeptide FragmentsToll-Like Receptor 4Alzheimer’s diseaseAmyloid betaCognitionNeuroinflammationNobiletinOxidative-nitrosative stress

Identifiers

PMID35294678
OpenAlexW4220898903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.