Evidence map›Paper›PMID 35294039›Full record

ArticleInternational journal of oncology2022

Spine‑specific downregulation of LAPTM5 expression promotes the progression and spinal metastasis of estrogen receptor‑positive breast cancer by activating glutamine‑dependent mTOR signaling.

Qingbing Meng, Lei Zhou, Haifeng Liang, Annan Hu, Hao Zhou, Jian Zhou, Xiaogang Zhou, Hong Lin, Xilei Li, Libo Jiang and 1 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Qingbing MengDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Lei ZhouDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Haifeng LiangDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Annan HuDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Hao ZhouDepartment of Orthopedic Surgery, Xuhui‑Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Jian ZhouDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Xiaogang ZhouDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Hong LinDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Xilei LiDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Libo JiangDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Jian DongDepartment of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Sun Yat-sen University · CNFudan University · CNZhongshan Hospital · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen receptor‑positive (ER

Indexed as

Breast NeoplasmsDown-RegulationFemaleGene Expression Regulation, NeoplasticGenes, Tumor SuppressorHumansMembrane ProteinsSignal TransductionLAPTM5 protein, humanMembrane ProteinsCX3CL1/CX3CR1estrogen receptor‑positive breast cancerglutamineLAPTM5mTORspinal metastasis

Identifiers

PMID35294039
PMCPMC8923652
OpenAlexW4220795824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.