Evidence map›Paper›PMID 35293864›Full record

ArticleeLife2022

Microtubule rescue at midzone edges promotes overlap stability and prevents spindle collapse during anaphase B.

Manuel Lera-Ramirez, François J Nédélec, Phong T Tran

Open access · greenAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Manuel Lera-RamirezInstitut Curie, PSL Research University, Sorbonne Université, CNRS UMR144, Paris, France.ORCID 0000-0002-8666-9746
François J NédélecSainsbury Laboratory, Cambridge University, Cambridge, United Kingdom.
Phong T TranInstitut Curie, PSL Research University, Sorbonne Université, CNRS UMR144, Paris, France.ORCID 0000-0002-2410-2277
Centre National de la Recherche Scientifique · FRUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage, unless microtubules grow to compensate sliding. How sliding and growth are coordinated is still poorly understood. In this study, we have used the fission yeast

Indexed as

AnaphaseSchizosaccharomycesMicrotubulesMitosisSpindle Apparatusanaphasecell biologylive cell imagingmicrotubule dynamicsmicrotubule slidingmodellingspindleS. pombe

Identifiers

PMID35293864
PMCPMC9018073
OpenAlexW4220976379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.