Evidence map›Paper›PMID 35293802›Full record

ArticleJournal of medical screening2022

Door-to-door hepatitis C screening in Georgia: An innovative model to increase testing and linkage to care.

Maia Butsashvili, Tamar Zurashvili, George Kamkamidze, Maia Kajaia, Lasha Gulbiani, Ana Gamezardashvili, Lia Gvinjilia, Tinatin Kuchuloria, Amiran Gamkrelidze, Shaun Shadaker and 3 more

Abstract read
In one paragraph

Article in Journal of medical screening, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Acceptability and Effectiveness of Point-of-Care HCV Testing in Low- and Middle-Income Countries: A Systematic Review.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. [The status of national and global hepatitis C elimination].Innere Medizin (Heidelberg, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maia ButsashviliHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.
Tamar ZurashviliHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.
George KamkamidzeHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.
Maia KajaiaHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.ORCID 0000-0002-0270-607X
Lasha GulbianiHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.
Ana GamezardashviliHealth Research Union/Clinic NEOLAB, Tbilisi, Georgia.
Lia GvinjiliaTEPHINET, Tbilisi, Georgia.
Tinatin KuchuloriaTEPHINET, Tbilisi, Georgia.
Amiran Gamkrelidze443716National Center for Disease Control and Public Health, Tbilisi, Georgia.
Shaun ShadakerDivision of Viral Hepatitis, 1242Centers for Disease Control and Prevention, Atlanta, GA, USA.
Muazzam NasrullahDivision of Viral Hepatitis, 1242Centers for Disease Control and Prevention, Atlanta, GA, USA.
Francisco AverhoffDivision of Viral Hepatitis, 1242Centers for Disease Control and Prevention, Atlanta, GA, USA.
Paige A ArmstrongDivision of Viral Hepatitis, 1242Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesGeorgia has a high prevalence of hepatitis C virus (HCV) infection. In 2015 a national HCV elimination program was launched providing free access to screening and treatment. To achieve elimination, innovative approaches to increase screening coverage and linkage to care are needed. This study estimates feasibility, acceptability, and outcomes of the door-to-door pilot HCV testing program in three cities.

methodsHouseholds were approached by system random sampling and all members were invited for study participation. Researchers used a detailed guide for conducting door-to-door testing and served as case navigators to link anti-HCV-positive individuals to care.

resultsTesting acceptance rate was high. In total 4804 individuals were tested and 48 (1.0%) were HCV positive. Among the entire sample of newly and previously tested individuals, overall HCV antibody prevalence was 3.6%. Through case navigation, of 48 newly identified and 26 previously identified anti-HCV-positive individuals, 42 (87.5%) and 17 (65.4%), respectively, were successfully linked to care.

conclusionsDoor-to-door HCV testing has potential to increase testing uptake. Such community-based approaches not only improve testing, but can also serve to increase linkage to care, which is important in achieving the goal of HCV elimination. The study provides a model for high prevalence countries aiming to eliminate hepatitis C.

Indexed as

Hepatitis CHepatitis C AntibodiesGeorgiaHepacivirusHumansMass ScreeningHepatitis C Antibodiesdoor-to-doorHCV screeninglinkage to care

Identifiers

PMID35293802
PMCPMC10068592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.