Evidence map›Paper›PMID 35293782›Full record

ArticleAntimicrobial agents and chemotherapy2022

Optimizing Vancomycin Dosing and Monitoring in Neonates and Infants Using Population Pharmacokinetic Modeling.

Praneeth Jarugula, Ayse Akcan-Arikan, Flor Munoz-Rivas, Brady S Moffett, Vijay Ivaturi, Danielle Rios

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Praneeth JarugulaCenter for Translational Medicine, Department of Pharmacy Practice and Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Ayse Akcan-ArikanBaylor College of Medicine, Houston, Texas, USA.
Flor Munoz-RivasBaylor College of Medicine, Houston, Texas, USA.
Brady S MoffettTexas Children's Hospital, The Woodlands, Texas, USA.ORCID 0000-0002-2221-2069
Vijay IvaturiCenter for Translational Medicine, Department of Pharmacy Practice and Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.ORCID 0000-0002-6433-1154
Danielle RiosUniversity of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA.
Baylor College of Medicine · USUniversity of Maryland, Baltimore · USTexas Children's Hospital · USUniversity of Iowa Stead Family Children’s Hospital · US

Funding

Postdoctoral training in Pediatric Clinical PharmacologyT32HD087969 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VAN DEN ANKER, JOHANNES NICOLAAS · 2016 to 2020
$998k
NICHD NIH HHS T32 HD087969
6 · The paper itself

Abstract

We determined optimal vancomycin starting dose regimens in infants ≤180 days of age to achieve the highest probability of target attainment with an area under the concentration-time curve for 24 h (AUC

Indexed as

Anti-Bacterial AgentsVancomycinAdultBody WeightChildComputer SimulationCreatinineFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesAnti-Bacterial AgentsCreatinineVancomycinneonatespediatricspharmacokineticsPK modelingvancomycin

Identifiers

PMID35293782
PMCPMC9046768
OpenAlexW4220951447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.