Evidence map›Paper›PMID 35293529›Full record

ArticleEinstein (Sao Paulo, Brazil)2022

What is the role of heat shock protein in abdominal organ transplantation?

Igor Lepski Calil, Francisco Tustumi, Jorge Henrique Bento de Sousa, Bruno Martins Tomazini, Ruy Jorge Cruz, Gustavo Niankowski Saliba, Rafael Antonio Arruda Pécora, Luiz Augusto Carneiro D'Albuquerque

Open access · diamondAbstract read
In one paragraph

Article in Einstein (Sao Paulo, Brazil), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Igor Lepski CalilHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7734-5491
Francisco TustumiFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6695-0496
Jorge Henrique Bento de SousaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6826-6823
Bruno Martins TomaziniHospital Sírio-Libanês, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6763-6132
Ruy Jorge CruzSchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-5290-9978
Gustavo Niankowski SalibaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-6613-2044
Rafael Antonio Arruda PécoraHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-5820-0828
Luiz Augusto Carneiro D'AlbuquerqueFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7607-7168
Hospital Israelita Albert Einstein · BRHospital Sírio-Libanês · BRUniversidade de São Paulo · BRUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes.

Indexed as

Organ TransplantationReperfusion InjuryHeat-Shock ProteinsHumansIschemiaHeat-Shock Proteins

Identifiers

PMID35293529
PMCPMC8909122
OpenAlexW4225784213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.