ArticleChemical communications (Cambridge, England)2022
Absolute configuration determination of pharmaceutical crystalline powders by MicroED
Article in Chemical communications (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED.Organic letters · 2024Article
- TAAM refinement on high-resolution experimental and simulated 3D ED/MicroED data for organic molecules.Acta crystallographica. Section C, Structural chemistry · 2024Article
- MicroED in drug discovery.Current opinion in structural biology · 2023Review
- Absolute Configuration Determination of Chiral API Molecules by MicroED Analysis of Cocrystal Powders Formed Based on Cocrystal Propensity Prediction Calculations.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Electron Diffraction of 3D Molecular Crystals.Chemical reviews · 2022Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Microcrystal electron diffraction (MicroED) has established its complementary role alongside X-ray diffraction in crystal structure elucidation. Unfortunately, kinematical refinement of MicroED data lacks the differentiation power to assign the absolute structure solely based on the measured intensities. Here we report a method for absolute configuration determination
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Registered trials
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