ArticleAmino acids2022
Dietary supplementation with monosodium glutamate enhances milk production by lactating sows and the growth of suckling piglets.
Article in Amino acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Glycine Supplementation Enhances the Growth of Sow-Reared Piglets with Intrauterine Growth Restriction.Animals : an open access journal from MDPI · 2025Article
- Glutamine and glutamate supplementation in sow diets during late gestation and lactation reduces farrowing duration, improves colostrum amino acid content, and enhances piglet weaning weight.Journal of animal science · 2025Article
- Effects of DietaryAnimals : an open access journal from MDPI · 2024Article
- Metabolism and Nutrition of L-Glutamate and L-Glutamine in Ruminants.Animals : an open access journal from MDPI · 2024Review
- Supplementing Monosodium Glutamate in Sow Diets Enhances Reproductive Performance in Lactating Sows and Improves the Growth of Suckling Piglets.Animals : an open access journal from MDPI · 2024Article
- Analysis of Gizzerosine in Foodstuffs by HPLC Involving Pre-column Derivatization with o-Phthaldialdehyde.Advances in experimental medicine and biology · 2024Article
- Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs with intrauterine growth restriction.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- Effects of Dietary Probiotics and Acidifiers on the Production Performance, Colostrum Components, Serum Antioxidant Activity and Hormone Levels, and Gene Expression in Mammary Tissue of Lactating Sows.Animals : an open access journal from MDPI · 2023Article
- Peculiarities in the Amino Acid Composition of Sow Colostrum and Milk, and Their Potential Relevance to Piglet Development.Veterinary sciences · 2023Article
- Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation.Amino acids · 2023Article
- Dietary glycine supplementation enhances postweaning growth and meat quality of pigs with intrauterine growth restriction.Journal of animal science · 2023Article
- Use of monosodium-glutamate as a novel dietary supplement strategy for ovarian stimulation in goats.Animal reproduction · 2023Article
- Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells.Amino acids · 2022Article
- Oxidation of amino acids, glucose, and fatty acids as metabolic fuels in enterocytes of developing pigs.Amino acids · 2022Article
- Dietary supplementation with branched-chain amino acids enhances milk production by lactating sows and the growth of suckling piglets.Journal of animal science and biotechnology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
This study was conducted to test the hypothesis that increasing dietary content of glutamate through addition of monosodium glutamate (MSG) enhances milk production by lactating sows and the growth of their offspring. Thirty multiparous sows (Landrace × Large White) were assigned randomly into one of three dietary groups: control (a corn- and soybean meal-based diet), the basal diet + 1% MSG, and the basal diet + 2% MSG. Diets were made isonitrogenous by the addition of appropriate amounts of L-alanine. Lactating sows had free access to drinking water and were fed twice daily their respective diets. The number of live-born piglets was standardized to 9 per sow at day 0 of lactation (the day of farrowing). On days 3, 15, and 29 of lactation, body weight and milk consumption of piglets were measured, and blood samples obtained from sows and piglets at 2 h and 1 h after feeding, respectively. Feed intake of sows did not differ (P > 0.05) among the three groups of sows. Concentrations of aspartate, glutamine, citrulline, arginine, tryptophan, proline, branched-chain amino acids, and glutamate were greater (P < 0.05) in the plasma of MSG-supplemented sows and their piglets than for controls. When compared with the control, dietary supplementation with 1-2% MSG increased (P < 0.05): concentrations of many free amino acids (including glutamate plus glutamine) and all protein-bound amino acids in milk; the milk intake of piglets by 14-25%; and daily weight gains of piglets by 23-44%. These results indicate that dietary supplementation with 1-2% MSG to lactating sows enhances milk production to support the growth of sow-reared piglets.
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Registered trials
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