Evidence map›Paper›PMID 35292850›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

The preventive care of medication-related osteonecrosis of the jaw (MRONJ): a position paper by Italian experts for dental hygienists.

Rodolfo Mauceri, Rita Coniglio, Antonia Abbinante, Paola Carcieri, Domenico Tomassi, Vera Panzarella, Olga Di Fede, Francesco Bertoldo, Vittorio Fusco, Alberto Bedogni and 1 more

Open access · hybridAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  7. [Expert consensus on perioperative management of tooth extraction in patients receiving denosumab therapy].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Article
  8. Pulling teeth: access to dental clearance in patients with cancer eligible for bone-modifying agents.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Rodolfo MauceriDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Via L. Giuffrè 5, 90127, Palermo, PA, Italy. rodolfo.mauceri@unipa.it.ORCID http://orcid.org/0000-0002-4008-6502
Rita ConiglioDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Via L. Giuffrè 5, 90127, Palermo, PA, Italy.ORCID http://orcid.org/0000-0003-4956-8556
Antonia AbbinanteItalian Dental Hygienists Association - AIDI, Aosta, Italy.ORCID http://orcid.org/0000-0003-4294-0941
Paola CarcieriDepartment of Surgical Sciences, CIR-Dental School, Oral Medicine Section, University of Turin, Turin, Italy.ORCID http://orcid.org/0000-0002-5501-8051
Domenico TomassiCatholic University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0001-5451-0602
Vera PanzarellaDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Via L. Giuffrè 5, 90127, Palermo, PA, Italy.ORCID http://orcid.org/0000-0001-6339-6020
Olga Di FedeDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Via L. Giuffrè 5, 90127, Palermo, PA, Italy.ORCID http://orcid.org/0000-0002-5562-7420
Francesco BertoldoDepartment of Medicine, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-5175-7340
Vittorio FuscoOncology Unit, Azienda Ospedaliera Di Alessandria SS, Antonio e Biagio E Cesare Arrigo, Alessandria, Italy.ORCID http://orcid.org/0000-0003-0263-9820
Alberto BedogniRegional Center for Prevention, Diagnosis and Treatment of Medication and Radiation-Related Bone Diseases of the Head and Neck, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0003-4742-4508
Giuseppina CampisiDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Via L. Giuffrè 5, 90127, Palermo, PA, Italy.ORCID http://orcid.org/0000-0002-9443-0495
University of Palermo · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITDepartment of Public Health · USUniversità Cattolica del Sacro Cuore · ITUniversity of Bari Aldo Moro · ITUniversity of Messina · ITUniversity of Padua · ITUniversity of Verona · IT

Funding

ministero dell'istruzione, dell'università e della ricerca PON-AIM line 1- Id. AIM1892002
6 · The paper itself

Abstract

purposeThe prevention and early diagnosis of medication-related osteonecrosis of the jaw (MRONJ) is fundamental to reducing the incidence and progression of MRONJ. Many in the field believe that dental hygienists should play an integral role in primary and secondary MRONJ prevention. However, to date, very few publications in the literature have proposed standardised MRONJ protocols, which are dedicated to dental hygienists. The aim of this study was to provide guidance to the health care providers managing MRONJ.

methodsThe expert opinion in this study was developed by dental hygienists from the main Italian technical-scientific associations (Italian Dental Hygienists Association, AIDI and National Union of Dental Hygienists, UNID) and authors of the latest Italian recommendations regarding MRONJ from the field of dentistry and maxillofacial surgery.

resultsThe oral care protocol outlined in this position paper is focused on the role of dental hygienist in patients at risk or affected by MRONJ, and it regards 3 main issues: primary prevention, secondary prevention and supporting the treatment of MRONJ. Each issue contains easy-to-apply indications and procedures, as described by the authors, regarding the role of the dental hygienist.

conclusionReferring to the main issues under consideration (primary prevention, secondary prevention and the treatment of MRONJ), a clinical examination of periodontal tissue is critical in preventing MRONJ. It is the opinion of the authors of this study that the application of a periodontal screening score is fundamental in defining personalised strategies for patients at risk of MRONJ. By means of these basic procedures, a protocol for assisting the health care provider and the presentation of a practical approach for patients at risk or affected by MRONJ are described in this study.

Indexed as

Bisphosphonate-Associated Osteonecrosis of the JawBone Density Conservation AgentsDental HygienistsDiphosphonatesHumansIncidenceBone Density Conservation AgentsDiphosphonatesDental hygienistsMRONJOsteonecrosis of the jawPeriodontal screening scorePreventionRisk factors

Identifiers

PMID35292850
PMCPMC9213300
OpenAlexW4221035472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.