Evidence map›Paper›PMID 35292706›Full record

ArticleScientific reports2022

Functionalization of an extended-gate field-effect transistor (EGFET) for bacteria detection.

Lea Könemund, Laurie Neumann, Felix Hirschberg, Rebekka Biedendieck, Dieter Jahn, Hans-Hermann Johannes, Wolfgang Kowalsky

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Lea KönemundInstitut für Hochfrequenztechnik, Technische Universität Braunschweig, 38106, Braunschweig, Germany.
Laurie NeumannInstitut für Hochfrequenztechnik, Technische Universität Braunschweig, 38106, Braunschweig, Germany.
Felix HirschbergInstitut für Hochfrequenztechnik, Technische Universität Braunschweig, 38106, Braunschweig, Germany.
Rebekka BiedendieckInstitute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, 38106, Braunschweig, Germany.
Dieter JahnInstitute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, 38106, Braunschweig, Germany.
Hans-Hermann JohannesInstitut für Hochfrequenztechnik, Technische Universität Braunschweig, 38106, Braunschweig, Germany. h2.johannes@ihf.tu-bs.de.
Wolfgang KowalskyInstitut für Hochfrequenztechnik, Technische Universität Braunschweig, 38106, Braunschweig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional sensing technologies have drawbacks as they are time-consuming, cost-intensive, and do not attain the required accuracy and reproducibility. Therefore, new methods of measurements are necessary to improve the detection of bacteria. Well-established electrical measurement methods can connect high sensitive sensing systems with biological requirements. One approach is to functionalize an extended-gate field-effect transistor's (EGFET) sensing area with modified porphyrins containing two different linkers. One linker connects the electrode surface with the porphyrin. The other linker bonds bacteria on the functional layer through a specific peptide chain. The negative charge on the surface of the cells regulates the surface potential which has an impact on the electrical behavior of the EGFET. The attendance of attached bacteria on the functionalized sensing area could successfully be detected.

Indexed as

Biosensing TechniquesBacteriaElectrodesReproducibility of ResultsTransistors, Electronic

Identifiers

PMID35292706
PMCPMC8924197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.