Evidence map›Paper›PMID 35292693›Full record

ArticleScientific reports2022

Cell segmentation for immunofluorescence multiplexed images using two-stage domain adaptation and weakly labeled data for pre-training.

Wenchao Han, Alison M Cheung, Martin J Yaffe, Anne L Martel

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Whole-Slide Imaging, Mutual Information Registration for Multiplex Immunohistochemistry and Immunofluorescence.Laboratory investigation; a journal of technical methods and pathology · 2023
    Article
  10. Article
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  13. Topological-Preserving Membrane Skeleton Segmentation in Multiplex Immunofluorescence Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wenchao HanBiomarker Imaging Research Laboratory, Sunnybrook Research Institute, Toronto, ON, Canada. wenchao.han@sri.utoronto.ca.
Alison M CheungBiomarker Imaging Research Laboratory, Sunnybrook Research Institute, Toronto, ON, Canada.
Martin J YaffeBiomarker Imaging Research Laboratory, Sunnybrook Research Institute, Toronto, ON, Canada.
Anne L MartelBiomarker Imaging Research Laboratory, Sunnybrook Research Institute, Toronto, ON, Canada.
Sunnybrook Hospital · CASunnybrook Research Institute

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular profiling with multiplexed immunofluorescence (MxIF) images can contribute to a more accurate patient stratification for immunotherapy. Accurate cell segmentation of the MxIF images is an essential step. We propose a deep learning pipeline to train a Mask R-CNN model (deep network) for cell segmentation using nuclear (DAPI) and membrane (Na

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerAnimalsFluorescent Antibody TechniqueHumansMiceSoftwareStaining and Labeling

Identifiers

PMID35292693
PMCPMC8924193
OpenAlexW4220748891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.