ArticleNature communications2022
A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 71 citations in OpenAlex.
- PmWRKY-10 Enhances Pine Wilt Disease Resistance by Promoting Pinosylvin Monomethyl Ether Biosynthesis Through Transcriptional Activation of PmPMT2-1.Molecular plant pathology · 2026Article
- Structural and mechanistic basis for the heterotetrameric benzaldehyde synthase from petunia.Science advances · 2026Article
- Benzyl alcohol biosynthesis and its subcellular compartmentalization enable scent formation and salicylic acid production.Nature communications · 2026Article
- Effect of Light Intensity on the Production of Volatile Organic Compounds by Submerged MacrophyteEcology and evolution · 2026Article
- Storage temperature modulates fruit quality, volatile compound profiles, and primary metabolite dynamics in 'Shijizhixing' peach.Food chemistry: X · 2026Article
- Antihypertensive Effects of Benzaldehyde in Rats: Involvement of Endothelium-Independent and Endothelium-Dependent Vasorelaxation via Prostacyclin (PGIPharmaceuticals (Basel, Switzerland) · 2026Article
- Physicochemical Characterization, In Vitro Anti-Aging Enzyme Modulation, and Dermocosmetic Application ofMolecules (Basel, Switzerland) · 2026Article
- A voyage of reprogrammable metabolic bioengineering reshapes plant defense: from editing tools to synthetic systems.Frontiers in plant science · 2026Review
- The Science behind vegetable aromas: types, synthesis, and influencing factors of volatile compounds.Plant signaling & behavior · 2025Review
- Enhancing the β-Oxidation-Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Effects of Wheat Composition on the Physicochemical and Volatile Components ofFoods (Basel, Switzerland) · 2025Article
- Salicylic acid biosynthesis via the PAL pathway requires benzaldehyde synthase and a benzyl salicylate-specific esterase.The Plant cell · 2025Article
- Peroxisomal-dependent signalling and dynamics modulate plant stress responses: reactive oxygen and nitrogen species as key molecules.Journal of experimental botany · 2025Review
- Article
- From data to discovery: leveraging big data in plant natural products biosynthesis research.The Plant journal : for cell and molecular biology · 2025Review
- UV-C-induced reactive carbonyl species are better detoxified in the halophytic plants Salicornia brachiata and Arthrocnemum macrostachyum than in the halophytic Sarcocornia fruticosa plants.The Plant journal : for cell and molecular biology · 2025Article
- Influence of Malted Chickpea on the Composition of Volatiles in Hummus.Molecules (Basel, Switzerland) · 2025Article
- Major Bioactive Compounds, Volatile and Sensory Profiles ofFoods (Basel, Switzerland) · 2025Article
- Comparative transcriptomic analysis of loquat floral fragrance and hormone synthesis regulation across developmental stages in petals and stamens.Frontiers in plant science · 2025Article
- Analysis ofMetabolites · 2024Article
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Authors and funding
4 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benzaldehyde, the simplest aromatic aldehyde, is one of the most wide-spread volatiles that serves as a pollinator attractant, flavor, and antifungal compound. However, the enzyme responsible for its formation in plants remains unknown. Using a combination of in vivo stable isotope labeling, classical biochemical, proteomics and genetic approaches, we show that in petunia benzaldehyde is synthesized via the β-oxidative pathway in peroxisomes by a heterodimeric enzyme consisting of α and β subunits, which belong to the NAD(P)-binding Rossmann-fold superfamily. Both subunits are alone catalytically inactive but, when mixed in equal amounts, form an active enzyme, which exhibits strict substrate specificity towards benzoyl-CoA and uses NADPH as a cofactor. Alpha subunits can form functional heterodimers with phylogenetically distant β subunits, but not all β subunits partner with α subunits, at least in Arabidopsis. Analysis of spatial, developmental and rhythmic expression of genes encoding α and β subunits revealed that expression of the gene for the α subunit likely plays a key role in regulating benzaldehyde biosynthesis.
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