ArticleObesity facts2022
Relationship between Birth Weight, Early Growth Rate, and Body Composition in 5- to 7-Year-Old Children.
Article in Obesity facts, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Anthropometry and Body Composition in Childhood: Follow-Up of a Randomised, Double-Blinded Controlled Trial With a Modified, Low-Protein Infant Formula During Infancy.Pediatric obesity · 2025Trial
- Birth weight impacts physical and motor performance of school-aged children in Matola, Mozambique.Scientific reports · 2025Article
- Genomic Selection for Early Growth Traits in Inner Mongolian Cashmere Goats Using ABLUP, GBLUP, and ssGBLUP Methods.Animals : an open access journal from MDPI · 2025Article
- Predicting low birth weight risks in pregnant women in Brazil using machine learning algorithms: data from the Araraquara cohort study.BMC pregnancy and childbirth · 2025Article
- Early adiposity rebound: predictors and outcomes.Italian journal of pediatrics · 2024Review
- Fetal overgrowth and weight trajectories during infancy and adiposity in early childhood.Pediatric research · 2024Article
- Growth Status of Full-Term Infants with Different Sizes for Gestational Age During the First Year of Life.Pediatric health, medicine and therapeutics · 2024Article
- Association between food environments and fetal growth in pregnant Brazilian women.BMC pregnancy and childbirth · 2023Article
- The association of intrauterine and postnatal growth patterns and nutritional status with toddler body composition.BMC pediatrics · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrograming of body composition during intrauterine growth may contribute to the higher risk for cardio-metabolic disease in individuals born small or large for gestational age (SGA, LGA). Compensations of intrauterine growth by catch-up or catch-down postnatal growth may lead to adverse consequences like a thin-fat phenotype.
methodsThe impact of (i) birth weight as well as (ii) the interaction between birth weight and catch-up or catch-down growth during the first 2 years of life on fat-free mass index (FFMI) and fat mass index (FMI) in 3,204 5-7-year-old children were investigated using Hattori's body composition chart. Body composition results were compared to appropriate for gestational age (AGA) birth weight with the same body mass index (BMI).
resultsIn total, 299 children at age 5-7 years were categorized as SGA, 2,583 as AGA, and 322 as LGA. When compared to AGA-children, BMI at 5-7 years of age was higher in LGA-children (15.5 vs. 16.2 kg/m2; p < 0.001) but not different in SGA-children. Compared to AGA with the same BMI, LGA was associated with higher FMI and a lower FFMI in 5-7-year-old girls. This phenotype was also seen for both sexes with catch-down growth during the first 2 years of life whereas catch-up growth prevented the higher FMI and lower FFMI per BMI. By contrast, SGA was associated with a higher FFMI and lower FMI in 5-7-year-old boys compared to AGA boys with the same BMI. This phenotype was also seen with catch-down growth in both genders whereas catch-up growth in girls led to more gain in FMI per BMI.
conclusionLGA with a compensatory catch-down postnatal growth may be a risk factor for the development of disproportionate gain in fat over lean mass whereas SGA with a catch-down postnatal growth seems to favor the subsequent accretion of lean over fat mass. A higher propensity of lean mass accretion during postnatal growth in boys compared to girls explains sex differences in these phenotypes.
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