Evidence map›Paper›PMID 35292542›Full record

ArticleBMJ case reports2022

Unusual cause of light chain cast nephropathy.

Kai Wen Chen, David Owen Rees, David Watson, Mared Owen-Casey

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kai Wen ChenNephrology Department, Betsi Cadwaladr University Health Board, Wrexham, UK kaiwenchen8@gmail.com.ORCID http://orcid.org/0000-0002-6092-3582
David Owen ReesNephrology Department, Betsi Cadwaladr University Health Board, Wrexham, UK.
David WatsonHaematology Department, Betsi Cadwaladr University Health Board, Wrexham, UK.
Mared Owen-CaseyHistopathology Department, Betsi Cadwaladr University Health Board, Rhyl, UK.
Betsi Cadwaladr University Health Board · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury due to light chain cast nephropathy is increasingly recognised in patients with haematological malignancies; however, the management and prognosis of this disease remain poorly understood. We describe a case of a 78-year-old woman with known chronic lymphocytic leukaemia (CLL) who presented with fatigue and weight loss. She was found to have acute kidney injury, which rapidly worsened during admission. Kidney biopsy showed light chain cast nephropathy and bone marrow biopsy confirmed B-cell CLL. She was started on ibrutinib, halting further deterioration in her renal function and avoiding renal replacement therapy in the first 8 months.

Indexed as

Acute Kidney InjuryHematologic NeoplasmsLeukemia, Lymphocytic, Chronic, B-CellAgedBiopsyFatigueFemaleHumansacute renal failurehaematology (drugs and medicines)haematology (incl blood transfusion)renal medicine

Identifiers

PMID35292542
PMCPMC8928313
OpenAlexW4220733611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.