Evidence map›Paper›PMID 35292537›Full record

ArticleLife science alliance2022

Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress.

Yoshitami Hashimoto, Hirofumi Tanaka

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Radiotherapy and radio-sensitization in H3CNS neuroscience & therapeutics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yoshitami HashimotoSchool of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan hashimo@toyaku.ac.jp.ORCID 0000-0002-8496-7846
Hirofumi TanakaSchool of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan.
Tokyo University of Pharmacy and Life Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mre11 is a versatile exo-/endonuclease involved in multiple aspects of DNA replication and repair, such as DSB end processing and checkpoint activation. We previously demonstrated that forced mitotic entry drives replisome disassembly at stalled replication forks in

Indexed as

DNA ReplicationExonucleasesAnimalsCell Cycle ProteinsProtein-Tyrosine KinasesXenopus laevisXenopus ProteinsCell Cycle ProteinsExonucleasesProtein-Tyrosine KinasesWEE1 protein, XenopusXenopus Proteins

Identifiers

PMID35292537
PMCPMC8924007
OpenAlexW4220771548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.