Evidence map›Paper›PMID 35292088›Full record

ArticleTrials2022

Electro-acupuncture for protracted amphetamine abstinence syndrome: study protocol for a pragmatic randomized controlled trial.

Huan Ren, Yiwei Zeng, Min Zhang, Su Zhang, Zhihan Chen, Binbin Wu, Jun Liu, Yulan Ren

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Huan RenSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Yiwei ZengSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Min ZhangSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Su ZhangSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Zhihan ChenSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China.
Binbin WuCoercive Rehabilitation Center for Addicts Affiliated to the Public Security Bureau of Deyang, Deyang, Sichuan, 618007, China.
Jun LiuMedical Rehabilitation Department, Drug Rehabilitation Administration of Sichuan Province, Chengdu, Sichuan, 610036, China.
Yulan RenSchool of Chinese Classics, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, China. renxg2468@163.com.
Chengdu University of Traditional Chinese Medicine · CNScience and Technology Department of Sichuan Province · CNShanghai Public Security Bureau · CN

Funding

Sichuan Province Science and Technology Support Program 2018SZ0071
6 · The paper itself

Abstract

backgroundProtracted amphetamine abstinence syndrome is one of the primary causes of relapse for amphetamine-type drug abusers during withdrawal. However, the importance of the management of protracted amphetamine abstinence syndrome is underestimated. Electro-acupuncture may be a safe and effective alternative therapy for protracted amphetamine abstinence syndrome, but the evidence is limited.

methodsThe study is a prospective, two-center, randomized, waitlist controlled, open-label pragmatic trial. A total of 300 patients with protracted amphetamine abstinence syndrome will be recruited. All participants will be randomly assigned to an electro-acupuncture group or a waitlist group in a 1:1 ratio. Participants in the electro-acupuncture group will receive the electrical-acupuncture treatment. Waitlist group participants will not receive electro-acupuncture treatment but will be assessed at each visit. Treatments will be administered twice a week for a total of 4 consecutive weeks. The primary outcome in this study is the change in the ACSA between baseline (week 0) and the completion of treatment (week 4), and the secondary outcomes are changes in the Hamilton Depression Scale (HAMD), the visual analog scale (VAS), the Hamilton Anxiety Scale (HAMA), the Pittsburgh Sleep Quality Index (PSQI), the Montreal Cognitive Assessment (MoCA), and the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). DISCUSSION: This study will assess the effectiveness of acupuncture in PAAS in real-world settings to provide support for clinical decisions and a basis for subsequent trials comparing acupuncture with other positive regimens.

trial registrationClinicalTrials.gov ChiCTR2000040619 . Registered on 3 December 2020.

Indexed as

Acupuncture TherapyAmphetamineHumansNeoplasm Recurrence, LocalPain MeasurementPragmatic Clinical Trials as TopicProspective StudiesRandomized Controlled Trials as TopicAmphetamineClinical trial protocolElectro-acupuncturePragmatic randomized controlled trials (pRCTs)Protracted amphetamine abstinence syndrome

Identifiers

PMID35292088
PMCPMC8922742
OpenAlexW4221066219

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.