ArticleBMC musculoskeletal disorders2022
Increase in tibial internal rotation due to weight-bearing is a key feature to diagnose early-stage knee osteoarthritis: a study with upright computed tomography.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Application of upright multidetector CT in orthopedics and the musculoskeletal system: insights into anatomy, alignment, and biomechanics.Japanese journal of radiology · 2026Review
- Characteristics of muscle morphological changes in the lower limb after total knee arthroplasty.International orthopaedics · 2026Article
- Review
- Article
- Weight-bearing computed tomography in knee pathologies: current evidence and future perspectives.Frontiers in surgery · 2026Review
- Off-axis biomechanical alterations and related interventions in medial knee osteoarthritis: a mini review.Frontiers in rehabilitation sciences · 2026Review
- Upright multidetector CT with 320-row gantry: a technical innovation providing insights into human anatomy under gravity and potential clinical implications.The British journal of radiology · 2025Article
- Equivalence assessment of weight bearing cone beam CT and multidetector CT through 3D Knee bone modelling.Scientific reports · 2025Article
- Recent trends in scientific research in chest radiology: What to do or not to do? That is the critical question in research.Japanese journal of radiology · 2025Review
- Future Applications of Cardiothoracic CT.Radiology · 2025Review
- Association of medial longitudinal arch height and stiffness with lower extremity alignment, pain, and disease severity in knee osteoarthritis: A cross-sectional study.Archives of rheumatology · 2024Article
- Trends in the Use of Weightbearing Computed Tomography.Journal of clinical medicine · 2024Review
- Quantitative assessment of the knee joint from weight bearing computed tomography.Osteoarthritis imaging · 2024Article
- CT in osteoarthritis: its clinical role and recent advances.Skeletal radiology · 2023Review
- Effect of knee joint weight change on knee function recovery and gait after total knee arthroplasty.BMC musculoskeletal disorders · 2022Article
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7 authors.
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Abstract
backgroundThe classification of knee osteoarthritis is an essential clinical issue, particularly in terms of diagnosing early knee osteoarthritis. However, the evaluation of three-dimensional limb alignment on two-dimensional radiographs is limited. This study evaluated the three-dimensional changes induced by weight-bearing in the alignments of lower limbs at various stages of knee osteoarthritis.
methodsForty five knees of 25 patients (69.9 ± 8.9 years) with knee OA were examined in the study. CT images of the entire leg were obtained in the supine and standing positions using conventional CT and 320-row detector upright CT, respectively. Next, the differences in the three-dimensional alignment of the entire leg in the supine and standing positions were obtained using 3D-3D surface registration technique, and those were compared for each Kellgren-Lawrence grade.
resultsGreater flexion, adduction, and tibial internal rotation were observed in the standing position, as opposed to the supine position. Kellgren-Lawrence grades 1 and 4 showed significant differences in flexion, adduction, and tibial internal rotation between two postures. Grades 2 and 4 showed significant differences in adduction, while grades 1 and 2, and 1 and 3 showed significant differences in tibial internal rotation between standing and supine positions.
conclusionsWeight-bearing makes greater the three-dimensional deformities in knees with osteoarthritis. Particularly, greater tibial internal rotation was observed in patients with grades 2 and 3 compared to those with grade 1. The greater tibial internal rotation due to weight-bearing is a key pathologic feature to detect early osteoarthritic change in knees undergoing osteoarthritis.
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