Evidence map›Paper›PMID 35291820›Full record

ArticleStroke2022

Simultaneous Hemodynamic and Structural Imaging of Ischemic Stroke With Magnetic Resonance Fingerprinting Arterial Spin Labeling.

Hongli Fan, Pan Su, Doris Da May Lin, Emily B Goldberg, Alexandra Walker, Richard Leigh, Argye E Hillis, Hanzhang Lu

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. "MR Fingerprinting for Imaging Brain Hemodynamics and Oxygenation".Journal of magnetic resonance imaging : JMRI · 2025
    Review
  5. Article
  6. Time-resolved MR fingerprinting for TMagnetic resonance in medicine · 2025
    Article
  7. Review
  8. Article
  9. Simultaneous perfusion, diffusion, TMagnetic resonance in medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hongli FanDepartment of Biomedical Engineering (H.F., H.L.), Johns Hopkins University School of Medicine, Baltimore, MD.
Pan SuThe Russell H. Morgan Department of Radiology and Radiological Science (H.F., P.S., D.D.M.L., H.L.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-6728-5878
Doris Da May LinThe Russell H. Morgan Department of Radiology and Radiological Science (H.F., P.S., D.D.M.L., H.L.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-6001-2383
Emily B GoldbergDepartment of Neurology (E.B.G., A.W., R.L., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.
Alexandra WalkerDepartment of Neurology (E.B.G., A.W., R.L., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-0522-3719
Richard LeighDepartment of Neurology (E.B.G., A.W., R.L., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-8285-1815
Argye E HillisDepartment of Neurology (E.B.G., A.W., R.L., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-5192-1171
Hanzhang LuDepartment of Biomedical Engineering (H.F., H.L.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0003-3871-1564
Johns Hopkins University · USKennedy Krieger Institute · US

Funding

Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
An integrated vascular MR imaging suite in brain diseasesR01NS106702 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2018 to 2022
$2.7M
Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkersUF1NS100588 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S., LU, HANZHANG · 2021 to 2021
$2.6M
Non-contrast MR imaging of blood-brain-barrier permeability in Alzheimer's diseaseR01AG064792 · NIA · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2020 to 2023
$2.6M
Blood-brain barrier dysfunction in Alzheimer's disease: from humans to animal modelsRF1AG071515 · NIA · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2021 to 2021
$2.4M
MR fingerprinting (MRF) perfusion imaging in cerebral vascular diseaseR01NS106711 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2018 to 2022
$2.2M
State of the Art 3T Research ScannerS10OD021648 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2016 to 2016
$2.0M
NIA NIH HHS R01 AG064792NIA NIH HHS RF1 AG071515NIBIB NIH HHS P41 EB031771NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466NIH HHS S10 OD021648NINDS NIH HHS R01 NS106702NINDS NIH HHS R01 NS106711NINDS NIH HHS UF1 NS100588
6 · The paper itself

Abstract

backgroundPerfusion and structural imaging play an important role in ischemic stroke. Magnetic resonance fingerprinting (MRF) arterial spin labeling (ASL) is a novel noninvasive method of ASL perfusion that allows simultaneous estimation of cerebral blood flow (CBF), bolus arrival time (BAT), and tissue T

methodsA total of 34 patients were scanned on 3T magnetic resonance imaging. MRF-ASL, standard single-delay pseudo-continuous ASL, T

resultsMRF-ASL derived parameters revealed a significant difference between stroke lesion and contralateral normal regions of interest, in that lesion regions manifested a lower CBF

conclusionsMRF-ASL may provide a new approach for quantitative hemodynamic and structural imaging in ischemic stroke.

Indexed as

Ischemic StrokeStrokeCerebrovascular CirculationCross-Sectional StudiesHemodynamicsHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopySpin LabelsSpin Labelshemodynamicsischemic strokemagnetic resonance imagingperfusiontissues

Identifiers

PMID35291820
PMCPMC9179092
OpenAlexW4220693391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.