Evidence map›Paper›PMID 35291755›Full record

ArticleGenetics research2022

Association of TNF-Alpha, MBL2, NOS2, and G6PD with Malaria Outcomes in People in Southern Ghana.

Godfred Fugtagbi, Paulina S Otu, Mubarak Abdul-Rahman, Ebenezer K Aidoo, Aminata C Lo, Ben A Gyan, Yaw A Afrane, Linda E Amoah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Godfred FugtagbiDepartment of Animal Biology and Conservation Science, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.
Paulina S OtuDepartment of Medical Microbiology, University of Ghana Medical School, University of Ghana, Accra, Ghana.
Mubarak Abdul-RahmanDepartment of Pathology, University of Ghana Medical School, University of Ghana, Accra, Ghana.ORCID 0000-0002-6684-5941
Ebenezer K AidooDepartment of Medical Laboratory, Accra Technical University, Accra, Ghana.
Aminata C LoImmunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0002-5010-1577
Ben A GyanImmunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0002-6154-4576
Yaw A AfraneDepartment of Medical Microbiology, University of Ghana Medical School, University of Ghana, Accra, Ghana.ORCID 0000-0001-5653-5993
Linda E AmoahImmunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.ORCID 0000-0002-1652-8489
University of Ghana · GHAccra Technical University · GH

Funding

Regional Centre for Vector Borne Diseases in West Africa (RCVBD)D43TW011513 · FIC · UNIVERSITY OF GHANA · PI YAW ASARE AFRANE, Guiyun Yan · 2021 to 2026
$1.5M
Impact of insecticide resistance on the behavior and fitness of malaria vectorsR01AI123074 · NIAID · UNIVERSITY OF GHANA · PI YAW ASARE AFRANE · 2016 to 2026
$1.2M
FIC NIH HHS D43 TW011513NIAID NIH HHS R01 AI123074
6 · The paper itself

Abstract

Background: One major issue that has set back the gains of the numerous malaria control interventions that national malaria control programs have implemented is asymptomatic malaria. Certain host genetic factors are known to influence symptomatic malaria; however, not much is known about how host genetics influences the acquisition of asymptomatic malaria. Methods: Genomic DNA was extracted from whole blood collected from 60 symptomatic and 149 nonfebrile (asymptomatic, Results: Polymorphisms at the MBL2 54 and TNF- Conclusion: Individuals in Southern Ghana carrying the TNF-

Indexed as

MalariaMalaria, FalciparumMannose-Binding LectinAdolescentAdultAgedAntigens, ProtozoanChildChild, PreschoolGhanaHumansMiddle AgedNitric Oxide Synthase Type IIPlasmodium falciparumProtozoan ProteinsTumor Necrosis Factor-alphaAntigens, ProtozoanMannose-Binding LectinMBL2 protein, humanNitric Oxide Synthase Type IINOS2 protein, humanProtozoan ProteinsTumor Necrosis Factor-alpha

Identifiers

PMID35291755
PMCPMC8901335
OpenAlexW4214774612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.