Evidence map›Paper›PMID 35291600›Full record

ArticleFrontiers in aging2021

Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against

Manmeet Bhalla, Roozbeh Nayerhoda, Essi Y I Tchalla, Alexsandra Abamonte, Dongwon Park, Shaunna R Simmons, Blaine A Pfeifer, Elsa N Bou Ghanem

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Manmeet BhallaDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Roozbeh NayerhodaDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Essi Y I TchallaDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Alexsandra AbamonteDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Dongwon ParkDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Shaunna R SimmonsDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Blaine A PfeiferDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Elsa N Bou GhanemDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
University at Buffalo, State University of New York · US

Funding

The role of neutrophils in the age-driven decline in anti-pneumococcal vaccine responsesR01AG068568 · NIA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BOU GHANEM, ELSA · 2021 to 2025
$2.0M
The efficacy of Liposomal Encapsulation of Polysaccharides pneumococcal vaccine in protecting aged hosts against invasive Streptococcus pneumoniae infections in murine modelsR21AG064215 · NIA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BOU GHANEM, ELSA, PFEIFER, BLAINE A. · 2019 to 2020
$436k
NIA NIH HHS R01 AG068568NIA NIH HHS R21 AG064215
6 · The paper itself

Abstract

Despite the availability of licensed vaccines, pneumococcal disease caused by the bacteria

Indexed as

agingantibodiesimmunosenescenceliposomespneumococcal diseasevaccines

Identifiers

PMID35291600
PMCPMC8920316
OpenAlexW4225516613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.