Evidence map›Paper›PMID 35291336›Full record

ArticleEuropean heart journal. Case reports2022

Fulminant Lyme myocarditis without any other signs of Lyme disease in a 37-year-old male patient with microscopic polyangiitis-a case report.

Marco R Schroeter, Karin Klingel, Peter Korsten, Gerd Hasenfuß

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Lyme carditis in Europe.Frontiers in microbiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marco R SchroeterDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Str. 40, D-37075 Göttingen, Germany.ORCID https://orcid.org/0000-0003-2514-1531
Karin KlingelCardiopathology, Institute for Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0003-0203-2498
Peter KorstenDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0001-6065-5680
Gerd HasenfußDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Str. 40, D-37075 Göttingen, Germany.ORCID https://orcid.org/0000-0002-5942-361X
Universitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lyme disease is a tick-borne multisystem infection. The most common cardiac manifestation is an acute presentation of Lyme carditis, which often manifests as conduction disorder and rarely as myocarditis. Case summary: We report the case of a 37-year-old male with a history of microscopic polyangiitis receiving immunosuppressive therapy. He was admitted for severe dyspnoea secondary to acute heart failure. Echocardiography and cardiac magnetic resonance imaging indicated a severely reduced left ventricular ejection fraction (LVEF) with global hypokinesia. Coronary heart disease was excluded, and endomyocardial biopsies (EMB) were performed. The left ventricular EMB revealed a rare case of fulminant Lyme carditis with evidence of typical lymphocytic myocarditis. Discussion: A severely reduced LVEF can be the primary manifestation of Lyme disease even without typical systemic findings and can have a favourable prognosis with antibiotic treatment. A thorough workup for Lyme carditis is required in patients with unexplained heart failure, particularly with EMB, especially in immunosuppressed patients.

Indexed as

Case reportEndomyocardial biopsyLyme carditisLyme diseaseMicroscopic polyangiitisMyocarditis

Identifiers

PMID35291336
PMCPMC8916016
OpenAlexW4210903625

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.