Evidence map›Paper›PMID 35291017›Full record

ArticleBiologia futura2022

The effects of bee venom on liver and skeletal muscle in exhaustive swimming rats.

Askin Senturk, Bahar Dalkiran, Burcu Acikgoz, Ilkay Aksu, Osman Acikgoz, Muge Kiray

Abstract read
PubMed Publisher
In one paragraph

Article in Biologia futura, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  2. Clinical complications in envenoming byFrontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Askin SenturkDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey.
Bahar DalkiranDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey.
Burcu AcikgozDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey.
Ilkay AksuDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey.
Osman AcikgozDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey.
Muge KirayDepartment of Physiology, Medical Faculty, Dokuz Eylul University, Balcova, Izmir, 35330, Turkey. muge.kiray@deu.edu.tr.ORCID http://orcid.org/0000-0001-5072-0100
Dokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative damage and proinflammatory cytokines are involved in exhaustive exercise-induced fatigue. This study aimed to investigate the effects of bee venom, a natural toxin, on fatigue and tissue damage in rats that underwent forced swimming exercise. Rats were divided into four groups: control, swimming exercise (SE), bee venom (BV) and swimming exercise + bee venom (SE + BV). SE and SE + BV groups were subjected to forced swimming (load of 7% body weight) for 5 days. BV and SE + BV groups were injected with 1 mg/kg BV subcutaneously. Swimming time, blood lactate and TNF-α levels, MDA and GSH levels in liver and gastrocnemius muscle were evaluated. Swimming time was shorter in SE + BV group than SE group. There was no difference in lactate levels between SE and SE + BV groups. MDA and GSH levels were increased in SE, BV and SE + BV groups. TNF-α levels were increased in BV group compared to control and SE groups. Our study demonstrated that BV administration before exhaustive exercise in rats did not provide anti-fatigue effect. Additionally, BV did not show anti-inflammatory activity and had different effects on antioxidant capacity at tissue level. Further research might explore the effects of different doses and durations of BV on exhaustive exercise.

Indexed as

Bee VenomsPhysical Conditioning, AnimalAnimalsLactatesLiverMuscle, SkeletalRatsSwimmingTumor Necrosis Factor-alphaBee VenomsLactatesTumor Necrosis Factor-alphaExhaustive exerciseInflammationLiverOxidative stressSkeletal muscle

Identifiers

PMID35291017
OpenAlexW4220957947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.