ArticleProceedings of the National Academy of Sciences of the United States of America1986
The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 71 citations in OpenAlex.
- Progress of non-small-cell lung cancer withFrontiers in molecular biosciences · 2023Review
- Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas.Translational lung cancer research · 2022Article
- Correlating ROS1 Protein Expression WithJTO clinical and research reports · 2021Article
- Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer.International journal of molecular sciences · 2021Review
- Recent Progress in Rare Oncogenic Drivers and Targeted Therapy For Non-Small Cell Lung Cancer.OncoTargets and therapy · 2019Review
- Recent Advances in Targeting ROS1 in Lung Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2017Review
- Crizotinib in ROS1-rearranged non-small-cell lung cancer.The New England journal of medicine · 2014Article
- Downregulation of ROS-FIG inhibits cell proliferation, colony‑formation, cell cycle progression, migration and invasion, while inducing apoptosis in intrahepatic cholangiocarcinoma cells.International journal of molecular medicine · 2014Article
- [Clinical significance of ROS1 rearrangements in non-small cell lung cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2013Review
- New targets in non-small cell lung cancer.Current oncology reports · 2013Review
- Activated RET and ROS: two new driver mutations in lung adenocarcinoma.Translational lung cancer research · 2013Review
- Targeted therapies in development for non-small cell lung cancer.Journal of carcinogenesis · 2013Review
- Novel targets in non-small cell lung cancer: ROS1 and RET fusions.The oncologist · 2013Review
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Mouse chromosome 10.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines.Proceedings of the National Academy of Sciences of the United States of America · 1988Article
- Genetic and cytogenetic changes in acute lymphoblastic leukemia.Medical oncology and tumor pharmacotherapy · 1988Review
- Expression and rearrangement of the ROS1 gene in human glioblastoma cells.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
- The molecular genetics of human chromosome 6.Journal of medical genetics · 1987Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone has been used to map the human c-ros homolog (ROS) to human chromosome region 6q16----6q22 by somatic cell hybrid analysis and chromosomal in situ hybridization. Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.