Evidence map›Paper›PMID 35290719›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.

Sheng-Chia Chung, Rui Providencia, Reecha Sofat, Mar Pujades-Rodriguez, Ana Torralbo, Ghazaleh Fatemifar, Natalie K Fitzpatrick, Julie Taylor, Ken Li, Caroline Dale and 4 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Sleep and dementia: Assessing established dementia-related factors using multivariable Mendelian randomization.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Inequalities in the burden of disease due to dementia, including Alzheimer disease, in British Columbia, Canada, from 2001 to 2022.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Health-Related Quality of Life among Older Adults with Dementia Living in Vietnamese Nursing Homes.International journal of environmental research and public health · 2024
    Article
  14. Article
  15. Review
  16. Has COVID-19 affected dementia diagnosis rates in England?International journal of geriatric psychiatry · 2023
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sheng-Chia ChungDepartment of Health Informatics, Health Data Research UK, London, UK.ORCID 0000-0001-6025-9207
Rui ProvidenciaBarts Health NHS Trust, London, UK.
Reecha SofatDepartment of Health Informatics, Health Data Research UK, London, UK.
Mar Pujades-RodriguezFaculty of Medicine, University of Leeds, London, UK.
Ana TorralboDepartment of Health Informatics, Health Data Research UK, London, UK.
Ghazaleh FatemifarDepartment of Health Informatics, Health Data Research UK, London, UK.
Natalie K FitzpatrickDepartment of Health Informatics, Health Data Research UK, London, UK.
Julie TaylorDepartment of Health Informatics, Health Data Research UK, London, UK.
Ken LiDepartment of Health Informatics, Health Data Research UK, London, UK.
Caroline DaleDepartment of Health Informatics, Health Data Research UK, London, UK.
Martin RossorDepartment of Neurodegeneration, UCL Institute of Neurology, London, UK.
Dionisio Acosta-MenaCegedim Health Data, Cegedim RX, London, UK.
John WhittakerGlaxoSmithKline, London, UK.
Spiros DenaxasDepartment of Health Informatics, Health Data Research UK, London, UK.

Funding

Medical Research Council MC_PC_20059Medical Research Council MR/K006584/1
6 · The paper itself

Abstract

introductionWe report dementia incidence, comorbidities, reasons for health-care visits, mortality, causes of death, and examined dementia patterns by relative deprivation in the UK.

methodA longitudinal cohort analysis of linked electronic health records from 4.3 million people in the UK was conducted to investigate dementia incidence and mortality. Reasons for hospitalization and causes of death were compared in individuals with and without dementia.

resultsFrom 1998 to 2016 we observed 145,319 (3.1%) individuals with incident dementia. Repeated hospitalizations among senior adults for infection, unknown morbidity, and multiple primary care visits for chronic pain were observed prior to dementia diagnosis. Multiple long-term conditions are present in half of the individuals at the time of diagnosis. Individuals living in high deprivation areas had higher dementia incidence and high fatality. DISCUSSION: There is a considerable disparity of dementia that informs priorities of prevention and provision of patient care.

Indexed as

DementiaElectronic Health RecordsAdultCohort StudiesHumansIncidenceMorbidityAlzheimer's diseasecause of deathcomorbiditydementiaelectronic health recordsepidemiologyhealth-care usehealth inequalityhospitalizationsincidencemortalityUnited Kingdomvascular dementia

Identifiers

PMID35290719
PMCPMC10078672

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.