Evidence map›Paper›PMID 35290707›Full record

ReviewHaemophilia : the official journal of the World Federation of Hemophilia2022

Osteoporosis management and falls prevention in patients with haemophilia: Review of haemophilia guidelines.

Madison J Petkovic, Huyen A Tran, Peter R Ebeling, Ayse Zengin

Open access · greenAbstract readReview
In one paragraph

Review in Haemophilia : the official journal of the World Federation of Hemophilia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The aging hemophilia patient.Hematology. American Society of Hematology. Education Program · 2025
    Review
  5. Article
  6. Review
  7. The influence of severity of hemophilia on bone mineral density and fracture risk.Research and practice in thrombosis and haemostasis · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Osteoporosis management and falls prevention in patients with haemophilia: Review of haemophilia guidelines.Haemophilia : the official journal of the World Federation of Hemophilia · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Madison J PetkovicDepartment of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Huyen A TranAustralian Centre for Blood Diseases, Monash University, Melbourne, Australia.
Peter R EbelingDepartment of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Ayse ZenginDepartment of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Monash Health · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with haemophilia (PWH) have a high prevalence of osteoporosis, falls and fractures at all ages. The role of haemophilia itself may contribute to low bone mineral density (BMD) due to coagulation factor deficiency. Guidelines for the management of osteoporosis, fracture and fall risk may help to reduce fracture and fall risk, and delay osteoporosis onset.

aimWe aim to review current haemophilia guidelines regarding osteoporosis prevention, screening, diagnosis and management, and fall prevention.

methodA database search (Ovid MEDLINE) revealed two haemophilia guidelines (World and British) published within the last ten years. Local Australian haemophilia guidelines were identified through a manual search.

resultsAll haemophilia guidelines were found to contain inadequate recommendations for osteoporosis management and fall prevention due to a lack of evidence in the literature.

conclusionFurther studies are required to assess the trajectory of bone health in PWH, the mechanism of bone loss in PWH, and the effectiveness of weight-bearing exercises, interventions for fall prevention, screening programmes, and use of anti-osteoporosis medications in PWH across the lifecourse.

Indexed as

Hemophilia AOsteoporosisAustraliaBone and BonesBone DensityHumansbone mineral densityfallfractureguidelinehaemophiliaosteoporosis

Identifiers

PMID35290707
PMCPMC9310867
OpenAlexW4220820987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.