Evidence map›Paper›PMID 35290604›Full record

ArticleCurrent medical science2022

Lymphocytes ≥ 2.9 (10

Hong-Mei Zhang, Xiao-Yong Li, Ning Lin, Yi-Xin Niu, Hong-Xia Gu, Shuai Lu, Zhen Yang, Li Qin, Qing Su

Abstract read
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In one paragraph

Article in Current medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Association of nocturnal hypoxemia and white blood cell count in a multicenter cohort.Sleep advances : a journal of the Sleep Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hong-Mei Zhang *Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Xiao-Yong Li *Department of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Ning LinDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Yi-Xin NiuDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Hong-Xia GuDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University (Chongming Branch), Shanghai, 202150, China.
Shuai LuDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University (Chongming Branch), Shanghai, 202150, China.
Zhen YangDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Li QinDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China. qinli@xinhuamed.com.cn.
Qing SuDepartment of Endocrinology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China. suqing@xinhuamed.com.cn.
XinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAtherosclerosis is considered a chronic inflammatory condition. The immune system is a key mediator in the initiation and progression of atherosclerosis. In a previous study, we found that the immune system was activated in diabetes and that total white blood cell (WBC) counts were elevated significantly in diabetic patients. To investigate whether WBC subtype counts in newly diagnosed diabetes are risk factors for future cardiovascular disease (CVD) events, we conducted a prospective population-based cohort study.

methodsA total of 1498 newly diagnosed diabetic patients aged 40 to 70 years old were followed up for three years. Participants with previous CVD history and abnormal WBC counts were excluded. CVD events were recorded during follow-up.

resultsWe found that the baseline lymphocyte counts were independently associated with cardiovascular events during follow-up, with the Exp (β) (95% CI) at 1.749 (1.084-2.821). Lymphocyte count ≥2.9 (10

conclusionWe concluded that even in a normal range, higher lymphocyte levels may result in a significantly higher CVD risk among diabetic patients. Lymphocyte count ≥2.9 (10

Indexed as

AtherosclerosisCardiovascular DiseasesDiabetes MellitusAdultAgedCohort StudiesHumansLymphocytesMiddle AgedProspective Studiescardiovascular eventsdiabeteslymphocytesrisk

Identifiers

PMID35290604
OpenAlexW4221015829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.