Evidence map›Paper›PMID 35290569›Full record

ArticleLa Radiologia medica2022

Comparison of point shear wave elastography and transient elastography in the evaluation of patients with NAFLD.

Giulio Argalia, Claudio Ventura, Niccolò Tosi, Daniele Campioni, Corrado Tagliati, Marianna Tufillaro, Monica Cucco, Gianluca Svegliati Baroni, Andrea Giovagnoni

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Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giulio ArgaliaDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy. giulio.argalia@gmail.com.ORCID http://orcid.org/0000-0001-5422-5625
Claudio VenturaDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Niccolò TosiDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Daniele CampioniDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Corrado TagliatiDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Marianna TufillaroDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Monica CuccoLiver Insult and Transplant Unit, Obesity Center, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Gianluca Svegliati BaroniLiver Insult and Transplant Unit, Obesity Center, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Andrea GiovagnoniDepartement of Radiological Sciences, Ospedali Riuniti Ancona, Università Politecnica Delle Marche, University Hospital, Via Tronto 10, 60126, Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare point shear wave elastography (pSWE, ElastPQ®) and transient elastography (TE) with Liver Biopsy in order to evaluate fibrosis stage in non-alcoholic fatty liver disease (NAFLD).

methodsOur prospective study from September 2017 to October 2020 included 50 consecutively enrolled patients with NAFLD (52.2 ± 13.0 years, 32 male). All patients underwent clinical evaluation, B-mode ultrasound, pSWE, TE and liver biopsy in a single evaluation. The clinical, laboratory and liver biopsy data were compared with liver stiffness (LS) measurement obtained with pSWE and TE. TE and pSWE diagnostic accuracy for the diagnosis of the different fibrosis stages were evaluated using the area under receiver operating characteristic curve (AUROC).

resultsOnly fibrosis stage was independently associated with TE and pSWE. The median liver stiffness measurement for fibrosis stages F0, F1, F2, F3, and F4 using TE was 4.8 (4.7-6.1) kPa, 5.5 (4.4-7.3) kPa, 7.7 (6.1-9.1) kPa, 9.9 (8.8-13.8) kPa, and 20.2 kPa, respectively. The corresponding median liver stiffness measurement using pSWE was 4.2 (4.0-4.8) kPa, 4.7 (4.2-5.8) kPa, 5.1 (4.1-6.9) kPa, 8.5 (5.2-13.3), and 15.1 kPa, respectively. The AUROC of TE for diagnosis of fibrosis stage F1, ≥ F2, ≥ F3, and F4 were 0.795, 0.867, 0.927, and 0.990, respectively. The corresponding AUROC of pSWE was 0.717, 0.733, 0.908, and 1.000, respectively. No association was observed with other histological parameters.

conclusionTE was significantly better than pSWE for the diagnosis of fibrosis stage ≥ F2. No statistically significant differences were found between TE and pSWE AUROC of fibrosis stage ≥ F1, ≥ F3, and F4.

Indexed as

Elasticity Imaging TechniquesNon-alcoholic Fatty Liver DiseaseBiopsyFibrosisHumansLiverLiver CirrhosisMaleProspective StudiesROC CurveLiver biopsyLiver stiffnessNon-alcoholic fatty liver diseasePoint shear wave elastographyTransient elastography

Identifiers

PMID35290569
OpenAlexW4221035713

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.