Evidence map›Paper›PMID 35290568›Full record

ArticleLa Radiologia medica2022

Intradiscal ozone therapy: fluoroscopic guidance reduces operative time in comparison with CT guidance in patients with lumbar disc herniation.

Francesco Somma, Gianluca Gatta, Alberto Negro, Mario Tortora, Gaetano Rea, Stefania Tamburrini, Gianvito Pace, Giuseppe Maria Ernesto La Tessa, Ferdinando Caranci, Vincenzo d'Agostino

Abstract read
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In one paragraph

Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Efficacy and safety of a modified ozone-mediated neurolysis in treatment for patients with resistant hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Trial
  2. Article
  3. Sex life and low back pain: The impact of intradiscal ozone therapy in patients with herniated lumbar disc.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Francesco SommaUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy. fra1585@hotmail.it.ORCID http://orcid.org/0000-0002-8193-3050
Gianluca GattaDipartimento Medicina di Precisione, Università Vanvitelli, Via de Crecchio, 80138, Napoli, Italy.ORCID http://orcid.org/0000-0003-0874-8294
Alberto NegroUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy.ORCID http://orcid.org/0000-0002-7904-1563
Mario TortoraDipartimento di Scienze Biomediche Avanzate, Università di Napoli Federico II, 80131, Napoli, Italy.ORCID http://orcid.org/0000-0002-4745-3061
Gaetano ReaUOC Radiologia, Ospedale Monaldi, AO dei Colli, Via Leonardo Bianchi, 80131, Napoli, Italy.ORCID http://orcid.org/0000-0002-5846-7872
Stefania TamburriniUOC Radiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy.ORCID http://orcid.org/0000-0003-0455-0256
Gianvito PaceUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy.ORCID http://orcid.org/0000-0002-2084-7976
Giuseppe Maria Ernesto La TessaUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy.ORCID http://orcid.org/0000-0002-2265-3067
Ferdinando CaranciDipartimento Medicina di Precisione, Università Vanvitelli, Via de Crecchio, 80138, Napoli, Italy.ORCID http://orcid.org/0000-0003-4381-8323
Vincenzo d'AgostinoUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Via Enrico Russo, 80147, Napoli, Italy.ORCID http://orcid.org/0000-0002-9011-0240
University of Campania "Luigi Vanvitelli" · ITCTO Hospital · ITOspedale Monaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare clinical success and operative time for percutaneous intradiscal ozone therapy in patients with lumbar disc herniation using fluoroscopic guidance versus computed tomography (CT). MATERIALS AND

methodsDuring the year 2019, 68 percutaneous single-level intradiscal ozone therapies were performed on patients complaining of low back pain and/or sciatica due to lumbar disc herniation, using fluoroscopic or conventional CT guidance, respectively, in 35 and 32 herniated lumbar discs, with at least 1-month follow-up. Oswestry Disability Index (ODI) was used to assess clinical outcome. Total room utilization time and procedure operative time were recorded for both fluoroscopy and CT guidance.

resultsFluoroscopy and CT groups were similar in terms of patient age (p value 0.45) and pre-procedure ODI (p value 0.64). Clinical success was obtained in 87.50% (28/32) patients in fluoroscopic group and 83.33% (30/36) in CT group. Mean total room utilization time was significantly longer for CT guidance (31.38 vs. 50.67 min, p < 0.0001), as well as the procedure operative time (15.94 vs. 27.61 min, p < 0.0001).

conclusionsCompared to conventional CT guidance, fluoroscopic guidance for percutaneous intradiscal ozone therapy in patients with lumbar disc herniation shows similar clinical success rates at 1-month follow-up, with decreased room utilization time and procedure operative time that implies less time consumption for medical and paramedical operative team.

Indexed as

Intervertebral Disc DisplacementOzoneFluoroscopyHumansLumbar VertebraeOperative TimeTomography, X-Ray ComputedTreatment OutcomeOzoneCT guidanceFluoroscopyIntradiscal therapyLow back painLumbar disc herniationOzone

Identifiers

PMID35290568
OpenAlexW4221034834

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.