Evidence map›Paper›PMID 35290521›Full record

ArticleJournal of cancer research and clinical oncology2023

Robotic stereotactic body radiotherapy for the management of adrenal gland metastases: a bi-institutional analysis.

Felix Ehret, David Kaul, Markus Kufeld, Clara Vom Endt, Volker Budach, Carolin Senger, Christoph Fürweger, Alfred Haidenberger, Alexander Muacevic

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Felix EhretBerlin Institute of Health at Charité-Universitätsmedizin Berlin, 10117, Berlin, Germany. felix.ehret@charite.de.ORCID http://orcid.org/0000-0001-6177-1755
David KaulDepartment of Radiation Oncology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 13353, Berlin, Germany.
Markus KufeldEuropean Radiosurgery Center, 81377, Munich, Germany.
Clara Vom EndtDepartment of Radiation Oncology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 13353, Berlin, Germany.
Volker BudachDepartment of Radiation Oncology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 13353, Berlin, Germany.
Carolin SengerDepartment of Radiation Oncology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 13353, Berlin, Germany.
Christoph FürwegerEuropean Radiosurgery Center, 81377, Munich, Germany.
Alfred HaidenbergerEuropean Radiosurgery Center, 81377, Munich, Germany.
Alexander MuacevicEuropean Radiosurgery Center, 81377, Munich, Germany.
Humboldt-Universität zu Berlin · DEGerman Cancer Research Center · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdrenal gland metastases (AGMs) are a common manifestation of metastatic tumor spread, especially in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). In patients with a limited systemic tumor burden, effective treatments for AGMs are needed. Due to varying fractionation schemes and limited reports, short-course treatment results for stereotactic body radiotherapy (SBRT) for AGMs are lacking. This work analyzes the outcomes of short-course SBRT for AGMs.

methodsPatients who underwent robotic SBRT for AGMs with one to five fractions were eligible for analysis.

resultsIn total, data from 55 patients with 72 AGMs from two institutions were analyzed. Most AGMs originated from renal cell carcinoma (38%) and NSCLC (35%). The median follow-up was 16.4 months. The median prescription dose and isodose line were 24 Gy and 70%, respectively. Most patients (85%) received SBRT with just one fraction. The median biologically effective dose assuming an α/β ratio of 10 (BED

conclusionRobotic SBRT is an efficient and safe treatment modality for AGM. Treatment-associated side effects are sporadic and manageable. Results suggest short-course SBRT to be a preferable and time-saving treatment option for the management of AGMs if an adequate BED

Indexed as

Adrenal Gland NeoplasmsCarcinoma, Non-Small-Cell LungKidney NeoplasmsLung NeoplasmsRadiosurgeryRobotic Surgical ProceduresAdrenal GlandsHumansRetrospective StudiesAdrenal glandAdrenal gland metastasisMetastasisOligometastasesSBRTStereotactic body radiotherapy

Identifiers

PMID35290521
PMCPMC9984319
OpenAlexW4220969577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.