Evidence map›Paper›PMID 35290390›Full record

ArticlePloS one2022

Radiation exposure and clinical outcome in patients undergoing percutaneous intradiscal ozone therapy for disc herniation: Fluoroscopic versus conventional CT guidance.

Francesco Somma, Vincenzo D'Agostino, Alberto Negro, Valeria Piscitelli, Stefania Tamburrini, Carmine Sicignano, Fabrizio Fasano, Silvio Peluso, Alessandro Villa, Gianvito Pace and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Sex life and low back pain: The impact of intradiscal ozone therapy in patients with herniated lumbar disc.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Francesco SommaUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.ORCID 0000-0002-8193-3050
Vincenzo D'AgostinoUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Alberto NegroUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Valeria PiscitelliUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Stefania TamburriniUOC Radiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.ORCID 0000-0003-0455-0256
Carmine SicignanoUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Fabrizio FasanoUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Silvio PelusoUOC Neurologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Alessandro VillaUOC Neurochirurgia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Gianvito PaceUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Giuseppe SartiUOC Radiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Giuseppe Maria Ernesto La TessaUOC Neuroradiologia, Ospedale del Mare, ASL NA 1 Centro, Napoli, Italy.
Giovanna PezzulloDipartimento Medicina di Precisione, Università "Vanvitelli", Napoli, Italy.
Gianluca GattaDipartimento Medicina di Precisione, Università "Vanvitelli", Napoli, Italy.
Ferdinando CaranciDipartimento Medicina di Precisione, Università "Vanvitelli", Napoli, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare technical success, clinical success, complications and radiation dose for percutaneous intradiscal ozone therapy in patients with lumbar disc herniation using fluoroscopic guidance versus conventional computed tomography (CT) guidance. MATERIALS AND

methodsBetween March 2018and March 2021, 124consecutive percutaneous intradiscal ozone therapies wereperformedon111 patients with low back pain (LBP) and/or sciatic pain due to lumbar disc herniation, using fluoroscopic or conventional CT guidance, respectively in 53 and 58 herniated lumbar discs, with at least 1-month follow up. Dose area product (DAP) and dose length product (DLP) were recorded respectively for fluoroscopy and CT, and converted to effective dose (ED).

resultsFluoroscopic and CT groups were similar in terms of patient age (p-value 0.39), patient weight (p-value 0.49) and pre-procedure Oswestry Disability Index (ODI, p-value 0.94). Technical success was achieved in all cases. Clinical success was obtained in 83.02% (44/53) patients in fluoroscopic group and 79.31% (46/58) in CT group. Mean DAP was 11.63Gy*cm2 (range 5.42-21.61). Mean DLP was 632.49mGy-cm (range 151.51-1699). ED was significantly lower in the fluoroscopic group compared toCT group (0.34 vs. 5.53mSv, p = 0.0119). No major complication was registered. Minor complications were observed in 4 cases (2 in fluoroscopic group; 2 in CT group).

conclusionsCompared to conventional CT guidance, fluoroscopic guidance for percutaneous intradiscal ozone therapy in patients with lumbar disc herniation shows similar technical and clinical success rates, with lower radiation dose. This technique helps sparing dose exposure to patients.

Indexed as

Intervertebral Disc DisplacementOzoneRadiation ExposureFluoroscopyHumansLumbar VertebraeRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeOzone

Identifiers

PMID35290390
PMCPMC8923460
OpenAlexW4221075561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.