Evidence map›Paper›PMID 35290293›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2022

Development of a Predictive Nomogram for Estimating Medication Nonadherence in Hemodialysis Patients.

Ying Wang, Yinhui Yao, Junhui Hu, Yingxue Lin, Chunhua Cai, Yanwu Zhao

Abstract readMulticenter Study
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying WangDepartment of Pharmacy, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).
Yinhui YaoDepartment of Pharmacy, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).
Junhui HuDepartment of Pharmacy, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).
Yingxue LinDepartment of Pharmacy, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).
Chunhua CaiDepartment of Patient Services, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).
Yanwu ZhaoDepartment of Pharmacy, Chengde Medical University Affiliated Hospital, Chengde, Hebei, China (mainland).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Medication compliance in hemodialysis patients affects the therapeutic effect of treatment and patient survival. Therefore, we aimed to explore the influencing factors of medication adherence in hemodialysis patients and develop a nomogram model to predict medication adherence. MATERIAL AND METHODS Data from questionnaires on medication adherence in hemodialysis patients were collected in Chengde from May 2020 to December 2020. The least absolute selection operator (LASSO) regression model and multivariable logistic regression analysis were used to analyze the risk factors for medication adherence in hemodialysis patients, and then a nomogram model was established. The bootstrap method was applied for internal validation. The concordance index (C-index), area under the receiver operating characteristic (ROC) curve (AUC), decision curve analysis (DCA), calibration curve, net reclassification improvement (NRI) index, and integrated discrimination improvement (IDI) index were used to evaluate the degree of differentiation and accuracy of the nomogram model, and clinical impact was used to investigate the potential clinical value of the nomogram model. RESULTS In total, 206 patients were included in this study, with a rate of medication nonadherence of 41.75%. Eight predictors were identified to build the nomogram model. The C-index, AUC, DCA, calibration curve, NRI, and IDI showed that the model had good discrimination and accuracy. The clinical impact plot showed that the nomogram of medication adherence in hemodialysis patients had clinical application value. CONCLUSIONS We developed and validated a nomogram model that is intuitive to apply for predicting medication adherence in hemodialysis patients.

Indexed as

Decision Support TechniquesDrug MonitoringNomogramsSEER ProgramAgedFemaleFollow-Up StudiesHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisRetrospective Studies

Identifiers

PMID35290293
PMCPMC8934011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.