Evidence map›Paper›PMID 35289968›Full record

SynthesisUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2022

Diagnostic accuracy of sliding sign for detecting pouch of Douglas obliteration and bowel involvement in women with suspected endometriosis: systematic review and meta-analysis.

J L Alcázar, P M Eguez, P Forcada, E Ternero, C Martínez, M Á Pascual, S Guerriero

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Comment on "Diagnostic Accuracy of Transvaginal Ultrasound for Detecting Pelvic Adhesions and Predicting Surgical Time in Benign Gynecologic Surgery".Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  2. Article
  3. Diagnostic Accuracy of Transvaginal Ultrasound for Detecting Pelvic Adhesions and Predicting Surgical Time in Benign Gynecologic Surgery.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Uterine "twisting sign": A new potential ultrasonographic soft marker for deep endometriosis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Observational
  8. Article
  9. Review
  10. Article
  11. Review
  12. Endometriosis MDC: role of the radiologist.Abdominal radiology (New York) · 2025
    Review
  13. Review
  14. Article
  15. Advances in Imaging for Assessing Pelvic Endometriosis.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

J L AlcázarDepartment of Obstetrics and Gynecology, Clínica Universidad de Navarra, Pamplona, Spain.ORCID 0000-0002-9700-0853
P M EguezDepartment of Obstetrics and Gynecology, University Hospital, Badajoz, Spain.
P ForcadaDepartment of Obstetrics and Gynecology, University Hospital, Castellón, Spain.
E TerneroDepartment of Obstetrics and Gynecology, Puerta de Mar University Hospital, Cadiz, Spain.
C MartínezDepartment of Obstetrics and Gynecology, La Fe University Hospital, Valencia, Spain.
M Á PascualDepartment of Obstetrics, Gynecology, and Reproduction, Hospital Universitari Dexeus, Barcelona, Spain.ORCID 0000-0001-5095-6981
S GuerrieroCentro Integrato di Procreazione Medicalmente Assistita e Diagnostica Ostetrico-Ginecologica, Azienda Ospedaliero Universitaria-Policlinico Duilio Casula Monserrato, Monserrato, Italy.ORCID 0000-0002-1359-7155
Centro de Implantología Cirugía Oral y Maxilofacial · ESClinica Universidad de Navarra · ESHospital General Universitari de Castelló · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Dexeus · ESHospital Universitario Puerta del Mar · ESUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this systematic review and meta-analysis was to evaluate the diagnostic accuracy of the sliding sign on transvaginal ultrasound (TVS) in detecting pouch of Douglas obliteration and bowel involvement in patients with suspected endometriosis, using laparoscopy as the reference standard.

methodsA search for studies evaluating the role of the sliding sign in the assessment of pouch of Douglas obliteration and/or bowel involvement using laparoscopy as the reference standard published from January 2000 to October 2021 was performed in PubMed/MEDLINE, Web of Science, CINAHL, The Cochrane Library, ClinicalTrials.gov and SCOPUS databases. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) was used to evaluate the quality of the studies. Analyses were performed using MIDAS and METANDI commands in STATA.

resultsA total of 334 citations were identified. Eight studies were included in the analysis, resulting in 938 and 963 patients available for analysis of the diagnostic accuracy of the sliding sign for pouch of Douglas obliteration and bowel involvement, respectively. The mean prevalence of pouch of Douglas obliteration was 37% and the mean prevalence of bowel involvement was 23%. The pooled estimated sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of the sliding sign on TVS for detecting pouch of Douglas obliteration were 88% (95% CI, 81-93%), 94% (95% CI, 91-96%), 15.3 (95% CI, 10.2-22.9), 0.12 (95% CI, 0.07-0.21) and 123 (95% CI, 62-244), respectively. The heterogeneity was moderate for sensitivity and low for specificity for detecting pouch of Douglas obliteration. The pooled estimated sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of the sliding sign on TVS for detecting bowel involvement were 81% (95% CI, 64-91%), 95% (95% CI, 91-97%), 16.0 (95% CI, 9.0-28.6), 0.20 (95% CI, 0.10-0.40) and 81 (95% CI, 34-191), respectively. The heterogeneity for the meta-analysis of diagnostic accuracy for bowel involvement was high.

conclusionThe sliding sign on TVS has good diagnostic performance for predicting pouch of Douglas obliteration and bowel involvement in women with suspected endometriosis. © 2022 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Indexed as

EndometriosisLaparoscopyDouglas' PouchFemaleHumansSensitivity and SpecificityUltrasonographybowelendometriosispouch of Douglassliding signsonography

Identifiers

PMID35289968
PMCPMC9825886
OpenAlexW4220761469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.