Evidence map›Paper›PMID 35289673›Full record

ArticleMicrobiology spectrum2022

A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals.

Xun Xiao, Hao Lu, Wentao Zhu, Yanqi Zhang, Xingchen Huo, Chunrong Yang, Shaobo Xiao, Yongan Zhang, Jianguo Su

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

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  14. A novel antimicrobial peptide screened by aFrontiers in immunology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xun XiaoDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Hao LuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Wentao ZhuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Yanqi ZhangDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Xingchen HuoDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Chunrong YangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Shaobo XiaoState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Yongan ZhangDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.
Jianguo SuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural Universitygrid.35155.37, Wuhan, China.ORCID 0000-0002-9083-0715
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type I interferons (IFN-Is) are critical antiviral cytokine in innate immunity but with limited direct defense ability against bacterial infections in mammals. In bony fish, despite all the IFN-Is (IFN1-4) act in antiviral immunity, studies demonstrate that IFN1 can remarkably contribute to host defense against bacterial infections. In this study, we found that IFN1 from grass carp (

Indexed as

Anti-Infective AgentsBacterial InfectionsCarpsEndotoxemiaInterferon Type IAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntimicrobial PeptidesAntiviral AgentsBacteriaLipopolysaccharidesMammalsMiceAnti-Bacterial AgentsAnti-Infective AgentsAnti-Inflammatory AgentsAntimicrobial PeptidesAntiviral AgentsInterferon Type ILipopolysaccharidesanti-inflammationantimicrobial peptidebactericidal activitygcIFN-20lipopolysaccharide neutralization

Identifiers

PMID35289673
PMCPMC9045357
OpenAlexW4221033898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.