ArticleEnvironmental health and preventive medicine2022
Abstaining from annual health check-ups is a predictor of advanced cancer diagnosis: a retrospective cohort study.
Article in Environmental health and preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 7 citations in OpenAlex.
- Psychometric properties and measurement invariance of the health behavior scale for cancer patients in Chinese cancer population.Health and quality of life outcomes · 2025Article
- The burden of thyroid cancer and its association with national development levels in Asia: evidence from 47 countries (1990-2021).Frontiers in oncology · 2025Article
- Priapism as an initial manifestation in an adult patient with chronic myeloid leukemia in Japan: case report and review of the literature.International cancer conference journal · 2024Article
- Factors associated with non-participation in breast cancer screening: analysis of the 2016 and 2019 comprehensive survey of living conditions in Japan.Breast cancer (Tokyo, Japan) · 2023Article
- Chronic morbidity levels and associated factors among older adults in western Nepal: A cross-sectional study.Journal of multimorbidity and comorbidityArticle
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Abstract
backgroundCancer prevention is a crucial challenge in preventive medicine. Several studies have suggested that voluntary health check-ups and recommendations from health professionals are associated with increased participation in cancer screening. In Japan, it is recommended that individuals aged 40-74 years should undergo annual health check-ups; however, the compliance to this recommendation is approximately <50%. According to the national survey, individuals who do not undergo annual health check-ups are at a higher risk for cancer. However, to the best of our knowledge, no previous study has investigated the association between the use of health check-ups and the incidence rate of cancer. We hypothesised that not undergoing periodic health check-ups and/or less use of outpatient medical services are predictors for advanced cancer.
methodsTo explore the relationship between health check-up or outpatient service utilisation and cancer incidence, this retrospective cohort study used data at two time points-baseline in 2014 and endpoint in 2017-from the National Health Insurance (NHI) claims and cancer registry. A multivariable logistic regression analysis was performed to investigate whether cancer diagnosis was associated with health check-up or outpatient service utilisation.
resultsA total of 72,171 participants were included in the analysis. The results of the multivariable logistic regression showed that individuals who skipped health check-ups had a higher risk of cancer diagnosis (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.04-1.40). Moreover, not undergoing health check-ups increased the risk of advanced-stage cancer (OR, 1.78; 95% CI, 1.29-2.44). Furthermore, increased rate of outpatient service utilisation was negatively associated with advanced cancer diagnosis.
conclusionsThis is the first study reporting that not undergoing health check-ups is a predictor of cancer diagnosis and advanced cancer stage. Primary prevention strategies for NHI members who do not undergo health check-ups must be reassessed. Moreover, future research should examine secondary prevention strategies, such as health education and recommendations from health professionals to facilitate adequate utilisation of preventive health services.
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