Evidence map›Paper›PMID 35289306›Full record

ArticleMolecules and cells2022

RIP3-Dependent Accumulation of Mitochondrial Superoxide Anions in TNF-α-Induced Necroptosis.

Jiyoung Lee, Sunmi Lee, Seongchun Min, Sang Won Kang

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiyoung LeeDepartment of Life Science, College of Natural Science, Ewha Womans University, Seoul 03760, Korea.ORCID https://orcid.org/0000-0001-6468-4366
Sunmi LeeDepartment of Life Science, College of Natural Science, Ewha Womans University, Seoul 03760, Korea.ORCID https://orcid.org/0000-0002-6477-7316
Seongchun MinDepartment of Life Science, College of Natural Science, Ewha Womans University, Seoul 03760, Korea.ORCID https://orcid.org/0000-0001-9410-5767
Sang Won KangDepartment of Life Science, College of Natural Science, Ewha Womans University, Seoul 03760, Korea.ORCID https://orcid.org/0000-0001-6446-163X
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive production of reactive oxygen species (ROS) is a key phenomenon in tumor necrosis factor (TNF)-α-induced cell death. However, the role of ROS in necroptosis remains mostly elusive. In this study, we show that TNF-α induces the mitochondrial accumulation of superoxide anions, not H

Indexed as

NecroptosisSuperoxidesApoptosisReactive Oxygen SpeciesReceptor-Interacting Protein Serine-Threonine KinasesTumor Necrosis Factor-alphaReactive Oxygen SpeciesReceptor-Interacting Protein Serine-Threonine KinasesSuperoxidesTumor Necrosis Factor-alphaNADPH oxidasenecroptosissuperoxide aniontumor necrosis factor-α

Identifiers

PMID35289306
PMCPMC9001146
OpenAlexW4221112936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.