ReviewNeuroscience and biobehavioral reviews2022
Hyper/neuroinflammation in COVID-19 and suicide etiopathogenesis: Hypothesis for a nefarious collision?
Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Toward a Unified Neuroimmune Framework for Infection-Associated Psychiatric Disorders.Diseases (Basel, Switzerland) · 2026Review
- Impact of chronic comorbidities on psychological and social status in COVID-19 patients.Frontiers in psychology · 2026Article
- Suicides in Tricity and Gdańsk County in 2010-2023: insights from demographic and toxicological data.Forensic sciences research · 2025Article
- COVID-19 and risk of self-harm, suicidal ideation, and poisoning in children and adolescents.Annals of medicine · 2025Article
- Risk of admission to hospital for self-harm after admission to hospital for COVID-19: French nationwide longitudinal study.BJPsych open · 2024Article
- Risk Factors for Suicidal Behavior in Youth and the Impact of SARS-CoV-2 Infection: A Retrospective Case-Control Study.medRxiv : the preprint server for health sciences · 2024Article
- Reactive Astrocytosis-A Potential Contributor to Increased Suicide in Long COVID-19 Patients?Brain sciences · 2024Review
- Risk of Suicide-Related Outcomes After SARS-COV-2 Infection: Results from a Nationwide Observational Matched Cohort of US Veterans.Journal of general internal medicine · 2024Article
- A Prospective Multicenter Longitudinal Analysis of Suicidal Ideation among Long-COVID-19 Patients.Healthcare (Basel, Switzerland) · 2024Article
- Suicide risk in patients with a current depressive episode during the COVID-19 pandemic.Frontiers in psychiatry · 2024Article
- Inflammatory pathology in depression and suicide: a mechanistic distillation of clinical correlates.Frontiers in immunology · 2024Review
- Evening Chronotype and Suicide: Exploring Neuroinflammation and Psychopathological Dimensions as Possible Bridging Factors-A Narrative Review.Brain sciences · 2023Review
- Review
- Association between Psychological, Biochemical and Personal Factors with the Inflammatory Marker High-Sensitive C Reactive Protein (Hs-CRP) in Mexican Healthy Population.Journal of personalized medicine · 2023Article
- Suicidality and homelessness: prevalence and associated factors of suicidal behaviour among homeless young adults in Southern Ethiopia.BMC psychology · 2023Article
- Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals.Brain, behavior, and immunity · 2023Article
- Suicidal ideation following self-reported COVID-19-like symptoms or serology-confirmed SARS-CoV-2 infection in France: A propensity score weighted analysis from a cohort study.PLoS medicine · 2023Article
- Suicide Risk in Post-COVID-19 Syndrome.Journal of personalized medicine · 2022Article
- C-Reactive Protein as a Potential Peripheral Biomarker for High-Lethality Suicide Attempts.Life (Basel, Switzerland) · 2022Article
- High molar ratios of tumor necrosis factorThe European journal of psychiatryArticle
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13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Accumulating scientific and clinical evidence highlighted pathological hyperinflammation as a cardinal feature of SARS-CoV-2 infection and acute COVID-19 disease. With the emergence of long COVID-19 syndrome, several chronic health consequences, including neuropsychiatric sequelae, have gained attention from the public and medical communities. Since inflammatory mediators have also been accredited as putative biomarkers of suicidal ideations and behaviors, hyper- and neuroinflammation might share some colliding points, overlapping and being interconnected in the context of COVID-19. This review aims to provide a summary of current knowledge on the molecular and cellular mechanisms of COVID-19-associated hyper/neuroinflammation with focus on their relevance to the inflammatory hypothesis of suicide development. Subsequently, strategies to alleviate COVID-19 hyper/neuroinflammation by immunomodulatory agents (many of which at experimental stages) as well as psychopharmacologic/psychotherapeutic approaches are also mentioned. While suicide risk in COVID-19 survivors - until now little known - needs further analysis through longitudinal studies, current observations and mechanistic postulates warrant additional attention to this possibly emerging mental health concern.
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