Evidence map›Paper›PMID 35289188›Full record

ArticleJournal of the American Heart Association2022

Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function.

Christian Staehr, Palle Duun Rohde, Nikolaj Thure Krarup, Steffen Ringgaard, Christoffer Laustsen, Jacob Johnsen, Rikke Nielsen, Hans Christian Beck, Jens Preben Morth, Karin Lykke-Hartmann and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Christian StaehrDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.ORCID 0000-0001-5431-4409
Palle Duun RohdeDepartment of Chemistry and Bioscience Aalborg University Aalborg Denmark.ORCID 0000-0003-4347-8656
Nikolaj Thure KrarupDepartment of Cardiology Viborg Regional Hospital Viborg Denmark.ORCID 0000-0001-6526-8663
Steffen RinggaardMR Research Centre Department of Clinical Medicine Aarhus University Aarhus Denmark.ORCID 0000-0001-5353-7379
Christoffer LaustsenMR Research Centre Department of Clinical Medicine Aarhus University Aarhus Denmark.ORCID 0000-0002-0317-2911
Jacob JohnsenDepartment of Clinical Medicine Aarhus University Aarhus Denmark.
Rikke NielsenDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.ORCID 0000-0003-3105-3474
Hans Christian BeckDepartment for Clinical Biochemistry and Pharmacology Odense University Hospital Odense Denmark.ORCID 0000-0002-7763-3637
Jens Preben MorthDepartment of Biotechnology and Biomedicine Technical University of Denmark Kgs. Lyngby Denmark.ORCID 0000-0003-4077-0192
Karin Lykke-HartmannDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.ORCID 0000-0002-6702-183X
Nichlas Riise JespersenDepartment of Clinical Medicine Aarhus University Aarhus Denmark.ORCID 0000-0003-2502-2102
Denis AbramochkinDepartment of Human and Animal Physiology Biological Faculty Lomonosov Moscow State University Moscow Russia.ORCID 0000-0001-5751-8853
Mette NyegaardDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.ORCID 0000-0003-4973-8543
Hans Erik BøtkerDepartment of Clinical Medicine Aarhus University Aarhus Denmark.ORCID 0000-0001-6358-8962
Christian AalkjaerDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.
Vladimir MatchkovDepartment of Biomedicine, Health Aarhus University Aarhus Denmark.ORCID 0000-0002-3303-1095
Aarhus University · DKAalborg University · DKLomonosov Moscow State University · RUOdense University Hospital · DKRegionshospitalet Viborg · DKTechnical University of Denmark · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Mutations in

Indexed as

HeartMigraine DisordersMigraine with AuraSodium-Potassium-Exchanging ATPaseAnimalsHeterozygoteMiceMutationMyocardiumAtp1a2 protein, mouseSodium-Potassium-Exchanging ATPaseheart failuremigrainemitochondrial functionNa,K‐ATPaseoxidative stress

Identifiers

PMID35289188
PMCPMC9075430
OpenAlexW4220834107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.