SynthesisJournal of biomedical optics2022
Signal-carrying speckle in optical coherence tomography: a methodological review on biomedical applications.
Synthesis in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Noise-aware dynamic convolution for improved generalizability of retinal disease diagnosis using optical coherence tomography images.Journal of biomedical optics · 2026Article
- Combination of tissue-derived and shape-based parameters for subclinical keratoconus detection.Biomedical optics express · 2026Article
- Label-free assessment of a microfluidic vessel-on-chip model with visible-light optical tomography reveals structural changes in vascular networks.Lab on a chip · 2026Article
- Convolutional Neural Networks Enable Direct Strain Estimation in Quasistatic Optical Coherence Elastography.Journal of biophotonics · 2025Article
- SpecstatOR: speckle statistics-based iOCT segmentation network for ophthalmic surgery.Biomedical optics express · 2025Article
- Optical coherence tomography for label-free detection and characterization of methicillin-resistantJournal of biomedical optics · 2025Article
- Auto-Segmentation and Quantification of Non-Cavitated Enamel Caries Imaged with Swept-Source Optical Coherence Tomography.Diagnostics (Basel, Switzerland) · 2023Article
- Observation of viscous liquid flow in tobacco substrate during heating using optical coherence tomography.Royal Society open science · 2023Article
- Speckle Contrast as Retinal Tissue Integrity Biomarker in Patients with Type 1 Diabetes Mellitus with No Retinopathy.Journal of personalized medicine · 2022Article
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Authors and funding
7 authors.
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Abstract
significanceSpeckle has historically been considered a source of noise in coherent light imaging. However, a number of works in optical coherence tomography (OCT) imaging have shown that speckle patterns may contain relevant information regarding subresolution and structural properties of the tissues from which it is originated.
aimThe objective of this work is to provide a comprehensive overview of the methods developed for retrieving speckle information in biomedical OCT applications. APPROACH: PubMed and Scopus databases were used to perform a systematic review on studies published until December 9, 2021. From 146 screened studies, 40 were eligible for this review.
resultsThe studies were clustered according to the nature of their analysis, namely static or dynamic, and all features were described and analyzed. The results show that features retrieved from speckle can be used successfully in different applications, such as classification and segmentation. However, the results also show that speckle analysis is highly application-dependant, and the best approach varies between applications.
conclusionsSeveral of the reviewed analyses were only performed in a theoretical context or using phantoms, showing that signal-carrying speckle analysis in OCT imaging is still in its early stage, and further work is needed to validate its applicability and reproducibility in a clinical context.
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