Evidence map›Paper›PMID 35289150›Full record

ArticleKorean journal of radiology2022

Development and Validation of

Xu Yang, Xia Lu, Jun Liu, Ying Kan, Wei Wang, Shuxin Zhang, Lei Liu, Jixia Li, Jigang Yang

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Development and validation ofQuantitative imaging in medicine and surgery · 2025
    Article
  5. Article
  6. Article
  7. Enhancing diagnostic precision in EBV-related HLH: a multifaceted approach usingCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  8. Article
  9. New Oncologic Imaging Section in theKorean journal of radiology · 2024
    Article
  10. Article
  11. Secondary hemophagocytic lymphohistiocytosis in children (Review).Experimental and therapeutic medicine · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Xu Yang *Department of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-7488-963X
Xia Lu *Department of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-2574-2281
Jun LiuDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-1907-8989
Ying KanDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-8115-6071
Wei WangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-8990-5516
Shuxin ZhangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-6946-3746
Lei LiuSinounion Medical Technology (Beijing) Co., Ltd., Beijing, China.ORCID 0000-0001-8268-2348
Jixia LiDepartment of Laboratory Medicine, School of Medicine, Foshan University, Foshan, China.ORCID 0000-0003-2218-5563
Jigang YangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China. yangjigang@ccmu.edu.cn.ORCID 0000-0002-0538-7676
Capital Medical University · CNFoshan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMATERIALS AND

methodsNinety-seven patients (age ≥ 14 years) with secondary HLH were retrospectively reviewed and divided into the derivation (n = 71) and validation (n = 26) cohorts according to admission time. In the derivation cohort, 22 patients had malignancy-associated HLH (M-HLH) and 49 patients had non-malignancy-associated HLH (NM-HLH). Data on pretreatment

resultsThe ratio of the maximal standardized uptake value (SUVmax) of the lymph nodes to that of the mediastinum, the ratio of the SUVmax of bone lesions or bone marrow to that of the mediastinum, and age were selected for constructing the model. The nomogram showed good performance in predicting M-HLH in the validation cohort, with an area under the receiver operating characteristic curve of 0.875 (95% confidence interval, 0.686-0.971). At an appropriate cutoff value, the sensitivity and specificity for identifying M-HLH were 90% (9/10) and 68.8% (11/16), respectively. The decision tree integrating the same variables showed 70% (7/10) sensitivity and 93.8% (15/16) specificity for identifying M-HLH. In comparison, visual analysis of

conclusion

Indexed as

Lymphohistiocytosis, HemophagocyticNeoplasmsAdolescentFluorodeoxyglucose F18HumansModels, StatisticalPositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesFluorodeoxyglucose F18DiagnosisHemophagocytic lymphohistiocytosisMalignancyPET-CT

Identifiers

PMID35289150
PMCPMC8961016
OpenAlexW4220945702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.