ArticleThe New phytologist2022
Predictive metabolomics of multiple Atacama plant species unveils a core set of generic metabolites for extreme climate resilience.
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed.
- Metabolic engineering of tobacco plants using Carica papaya NAC transcription factors: a biotechnology tool to improve plant metabolite production.Biotechnology letters · 2026Article
- Molecular and physiological characterization of two sunflower near-isogenic lines with contrasting haplotypes for leaf senescence.BMC plant biology · 2026Article
- Exploiting predictive metabolomics of pearl millet phenotypic traits using untargeted profiling across a Brazilian germplasm panel.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Assessment of phenotypic trait plasticity in the oilseed Camelina sativa using integrated early stage abiotic stress and field studies.Plant physiology · 2026Article
- Cold hardiness mechanisms and modeling: existing approaches and future avenues.The New phytologist · 2026Review
- Contrast in Mycorrhizal Associations Leads to Divergent Rhizosphere Metabolomes and Plant-Soil Feedback Among Grassland Species.Ecology letters · 2026Article
- Gramene 2025: expanded comparative genomics and pathway resources, integrated search, and pan-genome portals for crop research.Nucleic acids research · 2026Article
- Modeling the emergent metabolic potential of soil microbiomes in Atacama landscapes.Environmental microbiome · 2025Article
- Temporal-Resolution Dynamics of Polyphenolic During the Pepper Graft Healing.Plants (Basel, Switzerland) · 2025Article
- Interspecies predictions of growth traits from quantitative transcriptome data acquired during fruit development.Journal of experimental botany · 2025Article
- Integrated analysis of metabolites and enzyme activities reveals the plasticity of central carbon metabolism in grape (Horticulture research · 2025Article
- Untargeted metabolomics reveals anion and organ-specific metabolic responses of salinity tolerance in willow.The Plant journal : for cell and molecular biology · 2025Article
- Artificial intelligence: the human response to approach the complexity of big data in biology.GigaScience · 2025Review
- Grapevine cell response to carbon deficiency requires transcriptome and methylome reprogramming.Horticulture research · 2025Article
- Cardioprotective effects ofFrontiers in pharmacology · 2025Article
- Priming grapevines with oregano essential oil vapour results in a metabolomic shift eliciting resistance against downy mildew.BMC plant biology · 2024Article
- Article
- Metabolomics analysis reveals the metabolite profiles of Rheum tanguticum grown under different altitudinal gradients.BMC plant biology · 2024Article
- Biological and Chemical Characterization ofBiology · 2023Article
- Influences of chemotype and parental genotype on metabolic fingerprints of tansy plants uncovered by predictive metabolomics.Scientific reports · 2023Article
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15 authors.
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Abstract
Current crop yield of the best ideotypes is stagnating and threatened by climate change. In this scenario, understanding wild plant adaptations in extreme ecosystems offers an opportunity to learn about new mechanisms for resilience. Previous studies have shown species specificity for metabolites involved in plant adaptation to harsh environments. Here, we combined multispecies ecological metabolomics and machine learning-based generalized linear model predictions to link the metabolome to the plant environment in a set of 24 species belonging to 14 families growing along an altitudinal gradient in the Atacama Desert. Thirty-nine common compounds predicted the plant environment with 79% accuracy, thus establishing the plant metabolome as an excellent integrative predictor of environmental fluctuations. These metabolites were independent of the species and validated both statistically and biologically using an independent dataset from a different sampling year. Thereafter, using multiblock predictive regressions, metabolites were linked to climatic and edaphic stressors such as freezing temperature, water deficit and high solar irradiance. These findings indicate that plants from different evolutionary trajectories use a generic metabolic toolkit to face extreme environments. These core metabolites, also present in agronomic species, provide a unique metabolic goldmine for improving crop performances under abiotic pressure.
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