Spondyloarthritis in Senegal: a study of 770 cases.

Abbasse Abba, Moustapha Niasse, Ladji Mohamed Diaby, Hassan Ali

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Article in La Tunisie medicale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

What it found

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1 citing paper in PubMed, 0 citations in OpenAlex.

La Tunisie medicale
Article

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5 · Who and what money

Authors and funding

4 authors.

Abbasse Abba

Moustapha Niasse

Ladji Mohamed Diaby

Hassan Ali

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVery few studies have focused on spondyloarthritis (SpA) in sub-Saharan Africa. The majority of these studies have focused on series of HLA B27-negative SpA.

objectiveTo determine the epidemiological, diagnostic, therapeutic and evolutionary aspects of SpA in the rheumatology department of the CHU Aristide LeDantec in Dakar, Senegal.

methodsWe conducted a retrospective, descriptive, analytical study from January 1, 2012 to December 31, 2020, of patients with spondyloarthritis diagnosed according to the ESSG (54.5%), Amor (52.5%), modified New York criteria (48.3%) and ASAS (23%). For each patient, the following information was collected: sex, age, occupation, family history of spondyloarthritis in the parents, time to diagnosis, type of SpA.

results770 observations were collected from 273 men (35.5%) and 497 women (64.5%). Ankylosing spondylitis (AS) was the most frequent type of SpA in our series with 84% of cases. A biological inflammatory syndrome was present in 77.27% of our patients. HLA B27 phenotyping was performed in 437 patients, of which 225 were HLA B27 positive (51.48%). The majority of our patients were under conventional treatment due to the high cost of biotherapies which limits their prescription.

conclusionThe profile of SpA patients in our series was characterised by : the predominance of females, the later age of onset, the frequency of radiographic axial forms of SpA and the biological inflammatory syndrome. HLA B27 was present in one patient out of two, as in the North African series.

Indexed as

SpondylarthritisFemaleHLA-B27 AntigenHumansMaleRetrospective StudiesSenegalHLA-B27 Antigen

Identifiers

PMID35288897

PMCPMC8972174

OpenAlexW4287544351

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