Evidence map›Paper›PMID 35288863›Full record

ReviewJournal of gastrointestinal cancer2023

Risk of Cancer in Inflammatory Bowel Disease and Pitfalls in Oncologic Therapy.

Renata D Peixoto, Artur R Ferreira, James M Cleary, João P Fogacci, João P Vasconcelos, Alexandre A Jácome

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Rectal Cancer and Radiation in Colitis.Clinics in colon and rectal surgery · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Renata D PeixotoInstituto Oncoclínicas, São Paulo, SP, Brazil. renatadalpino@gmail.com.ORCID http://orcid.org/0000-0003-0053-7951
Artur R FerreiraInstituto Oncoclínicas, São Paulo, SP, Brazil.
James M ClearyDana farber cancer institute, Boston, MA, 02215, USA.
João P FogacciInstituto Oncoclínicas, São Paulo, SP, Brazil.
João P VasconcelosInstituto Oncoclínicas, São Paulo, SP, Brazil.
Alexandre A JácomeInstituto Oncoclínicas, São Paulo, SP, Brazil.
Instituto de Oncologia do Paraná · BRDana-Farber Cancer Institute · USInstituto Biológico · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD), represented by ulcerative colitis and Crohn's disease, is an idiopathic condition caused by a dysregulated immune response to host intestinal microflora, leading to chronic relapsing intestinal inflammation. Individuals with IBD are more prone to die from several diseases, including cancer.

methodsAn extensive search was conducted of PubMed using the following medical subject heading-"inflammatory bowel disease" OR "Crohn's disease" OR "ulcerative colitis" AND "cancer."

resultsIn this review article, we discuss the oncogenic mechanisms and genomics of colitis-associated colorectal cancer. Beyond this, we describe the multiple other malignancies that IBD patients are at risk for, discuss caveats in the screening and diagnosis of those cancers, and shed light on pitfalls on the management and treatment of cancer in IBD patients.

conclusionPatients, caregivers, and health professionals who deal with IBD must be educated on how to identify warning signs so that cancers can be diagnosed and treated as early as possible.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesNeoplasmsHumansCancer riskCancer treatmentInflammatory bowel disease

Identifiers

PMID35288863
OpenAlexW4221026590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.