Evidence map›Paper›PMID 35288668›Full record

ArticleNature biotechnology2022

m

Lulu Hu, Shun Liu, Yong Peng, Ruiqi Ge, Rui Su, Chamara Senevirathne, Bryan T Harada, Qing Dai, Jiangbo Wei, Lisheng Zhang and 8 more

Erratum issuedAbstract read
In one paragraph

Article in Nature biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 176 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Optimized GLORI-Seq of Chromatin-Associated RNAs.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  3. Review
  4. Review
  5. Review
  6. mNature reviews. Neuroscience · 2026
    Review
  7. Article
  8. Single-nucleotide RNA mCell reports · 2026
    Article
  9. Article
  10. WTAP-Mediated mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Review
  13. The Role of NMedComm · 2026
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. FTO separation-of-function mutations alter mbioRxiv : the preprint server for biology · 2026
    Article
  20. Article

116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Lulu Hu *Department of Chemistry, The University of Chicago, Chicago, IL, USA. luluhu@fudan.edu.cn.ORCID http://orcid.org/0000-0001-7246-1736
Shun Liu *Department of Chemistry, The University of Chicago, Chicago, IL, USA.
Yong Peng *Department of Chemistry, The University of Chicago, Chicago, IL, USA.
Ruiqi Ge *Department of Chemistry, The University of Chicago, Chicago, IL, USA.
Rui Su *Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA.ORCID http://orcid.org/0000-0002-4807-6229
Chamara SenevirathneChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bryan T HaradaDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-9683-782X
Qing DaiDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-8578-1568
Jiangbo WeiDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-2691-6490
Lisheng ZhangDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Ziyang HaoDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Liangzhi LuoDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Huanyu WangDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Yuru WangDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Minkui LuoChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-7409-7034
Mengjie ChenSection of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA. mengjiechen@uchicago.edu.ORCID http://orcid.org/0000-0003-1579-087X
Jianjun ChenDepartment of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA. jianchen@coh.org.ORCID http://orcid.org/0000-0003-3749-2902
Chuan HeDepartment of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
CANCER PHARMACOLOGYT32CA062948 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORRAINE J GUDAS · 1994 to 2026
$12.1M
Interrogating Protein Methyltransferases with Integrated ApproachesR35GM131858 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Minkui Luo · 2019 to 2026
$6.3M
New directions in single cell genomics method developmentR01GM126553 · NIGMS · UNIVERSITY OF CHICAGO · PI Mengjie Chen · 2017 to 2026
$2.9M
The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemiaR01CA271497 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Jianjun Chen · 2022 to 2026
$2.8M
Targeting FTO to treat acute myeloid leukemiaR01CA243386 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2020 to 2024
$2.8M
TET2-mediated epitranscriptomic regulation in leukemia microenvironmentR01CA280389 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Jianjun Chen · 2023 to 2026
$2.7M
The role and mechanism of METTL3/METTL14-mediated RNA modification in the pathogenesis and drug-resistance of AMLR01CA236399 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2019 to 2023
$2.3M
Targeting TET1 signaling to treat acute myeloid leukemiaR01CA211614 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.3M
The function and underlying mechanism of TET1 in myelodysplastic syndromesR01DK124116 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2020 to 2023
$2.2M
The role and mechanism of FTO in leukemogenesis and drug responseR01CA214965 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.1M
Howard Hughes Medical InstituteNCI NIH HHS F32 CA221007NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA211614NCI NIH HHS R01 CA214965NCI NIH HHS R01 CA236399NCI NIH HHS R01 CA243386NCI NIH HHS R01 CA271497NCI NIH HHS R01 CA280389NCI NIH HHS T32 CA062948NHGRI NIH HHS R01 HG012927NHGRI NIH HHS RM1 HG008935NIDDK NIH HHS R01 DK124116NIGMS NIH HHS R01 GM126553NIGMS NIH HHS R35 GM131858
6 · The paper itself

Abstract

Functional studies of the RNA N

Indexed as

RNA Processing, Post-TranscriptionalTranscriptomeAnimalsHumansMammalsMethylationRNARNA, MessengerRNARNA, Messenger

Identifiers

PMID35288668
PMCPMC9378555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.